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It is well-established that women's nutrition knowledge (NK) is strongly associated with children's nutritional outcomes. However, the association of women's NK with their own diet and health status, including cancer occurrence, remains unknown. This case-control study aimed to assess the associations of NK with dietary patterns (DPs) and breast cancer (BC) occurrence in peri- and postmenopausal women. Data were collected for 417 women aged 40.0-79.9 years from north-eastern Poland, including 189 BC cases. The Dietary Habits and Nutrition Beliefs Questionnaire (QEB) was used to assess NK. Based on the dietary data collected with a food frequency questionnaire (62-item FFQ-6), the three DPs were previously identified, and the Polish-adapted Mediterranean Diet (Polish-aMED) score was calculated. The odds ratio of BC occurrence was lower at the higher level of NK (16-25 points) by 49% (p = 0.0280) compared to the lower level of NK (0-12 points). A higher level of NK was associated with higher adherence to the 'Prudent' pattern and the Polish-aMED score, as well as with lower adherence to the 'Western' and the 'Processed plant fats and sweetened dairy' patterns compared to the lower level of NK. In conclusion, the high level of nutrition-related knowledge seems to be associated with pro-healthy food choices and cancer prevention. Due to the case-control design of the present study and potential reverse causation, there is a need to confirm the obtained findings in further longitudinal studies.
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http://dx.doi.org/10.1038/s41598-025-09931-x | DOI Listing |
Dan Med J
August 2025
Psychiatry, Aalborg University Hospital, Aalborg.
People with severe mental illness die 10-20 years earlier than the general population, mostly from preventable physical diseases. Fragmented care, under-screening and undertreatment of cardiovascular, respiratory, infectious and cancer conditions widen this gap. Embedding physical screening, proactive treatment, smoking cessation, cancer checks and multidisciplinary, person-centred care into psychiatric services could close this mortality divide.
View Article and Find Full Text PDFMed Trop Sante Int
July 2025
Unité des maladies infectieuses et tropicales et CIC Inserm 1424, Centre hospitalier de Cayenne, Cayenne, Guyane.
Tahiti or the "myth of Paradise", Bora Bora, "the Pearl of the Pacific". Who has never wanted to take a plane and come and land on the heavenly beaches of Polynesia, a French territory at the antipodes of mainland France lost in the middle of the Pacific? However, we do not imagine that 60% of Polynesians live below the metropolitan low-income threshold or that life expectancy is lower than that of the mainland due to the high prevalence of cardiovascular diseases with three quarters overweight population.In addition to non-transmissible metabolic diseases, various pathologies common to temperate countries present specificities in Polynesia, leading to sometimes different management and medical reasoning.
View Article and Find Full Text PDFFront Immunol
September 2025
Precision Pharmacy and Drug Development Center, Department of Pharmacy, Tangdu Hospital, Fourth Military Medical University, Xi'an, Shaanxi, China.
Gliomas are the most common primary malignant tumors of the central nervous system (CNS), and despite progress in molecular diagnostics and targeted therapies, their prognosis remains poor. In recent years, immunotherapy has emerged as a promising treatment modality in cancer therapy. However, the inevitable immune evasion by tumor cells is a key barrier affecting therapeutic efficacy.
View Article and Find Full Text PDFFront Immunol
September 2025
Department of Medicine, Division of Hematology, Bioclinicum and Center for Molecular Medicine, Karolinska Institute and Karolinska University Hospital Solna, Stockholm, Sweden.
Background: Metabolic reprogramming is an important hallmark of cervical cancer (CC), and extensive studies have provided important information for translational and clinical oncology. Here we sought to determine metabolic association with molecular aberrations, telomere maintenance and outcomes in CC.
Methods: RNA sequencing data from TCGA cohort of CC was analyzed for their metabolic gene expression profile and consensus clustering was then performed to classify tumors into different groups/subtypes.
Biochem Biophys Rep
December 2025
Division of Breast Surgery, Department of Surgery, Taipei Veterans General Hospital, Taipei, 112, Taiwan.
Purpose: This study aimed to conduct functional proteomics across breast cancer subtypes with bioinformatics analyses.
Methods: Candidate proteins were identified using nanoscale liquid chromatography with tandem mass spectrometry (NanoLC-MS/MS) from core needle biopsy samples of early stage (0-III) breast cancers, followed by external validation with public domain gene-expression datasets (TCGA TARGET GTEx and TCGA BRCA).
Results: Seventeen proteins demonstrated significantly differential expression and protein-protein interaction (PPI) found the strong networks including COL2A1, COL11A1, COL6A1, COL6A2, THBS1 and LUM.