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Article Abstract
Objective: Solomon Islands, a Western Pacific nation, faces a growing burden of type II diabetes amid chronic healthcare shortages. Surgeons report increased incidence of diabetic amputations; however, data on infection rates and pathology remain scarce. This study describes the microbiology of diabetic ulcers in cases of major limb amputation.
Method: Demographic, microbiological and outcome data were extracted from records of patients with diabetes who underwent major limb amputation from 2018-2023 in Solomon Islands.
Results: Among 356 adults who underwent major limb amputation, microbiological data were available for 113 (32%). Pus and tissue cultures identified 20 bacterial species-predominantly (n=27; 24%), mixed enteric organisms (n=25; 23%) and (n=18; 16%). Meticillin-resistant was identified in one patient. Antibiotic resistance was observed in 62 (55%) cultures, with the highest resistance rates against: ampicillin (31 cases); amoxicillin (31 cases); gentamicin (21 cases); and trimethoprim/sulfamethoxazole (21 cases). and spp. were significantly associated with resistance.
Conclusion: The bacterial diversity and high resistance rates identified in this study are concerning given limited access to next-generation antibiotics in Solomon Islands. Further research is needed to evaluate infection management, resistance drivers and clinical outcomes of antibiotic-resistant infections in Solomon Islands.
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| http://dx.doi.org/10.12968/jowc.2025.0201 | DOI Listing |
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