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Background Diabetic foot disease is a significant cause of morbidity among individuals with diabetes and can be effectively prevented with proper patient education early in the disease course. This study was conducted with the aim of assessing the knowledge, attitudes, and practices of diabetic patients toward foot care, as well as estimating the prevalence of diabetic foot disease. Methods A cross-sectional study was conducted among 128 diagnosed patients with diabetes, using a structured questionnaire and the Michigan Neuropathy Screening Instrument (MNSI) parts A and B, at a referral hospital in Central India. The questionnaire included questions about foot care practices, knowledge of diabetic foot complications, and attitudes toward foot care. The MNSI was used to screen for neuropathic symptoms and signs indicative of diabetic foot disease. Results Among the participants, 110 out of 128 (85.9%) reported that they had never received any education from their healthcare provider regarding proper foot care practices. Almost one-fourth of our participants, accounting for 95 (74.2%) of them, lacked adequate knowledge about maintaining proper foot hygiene, and 78 (60.9%) were unaware of the foot-related complications associated with diabetes. The study found a significant positive association between knowledge scores and the duration of diabetes. Despite the lack of knowledge, 125 (97%) of the patients demonstrated a positive attitude and expressed a willingness to adopt proper practices when educated. Notably, 52 (40.6%) of the participants walked barefoot, and 116 (90.6%) did not undergo annual foot examinations. Diabetic foot disease was identified in 40 out of 128 (31.3%) participants based on abnormal MNSI scores. There was a significant positive correlation between the duration of diabetes and the presence of diabetic foot disease. Higher MNSI score A was associated with poorly controlled diabetes, highlighting the impact of glycemic control on neuropathic symptoms. The presence of diabetic foot disease was also significantly associated with macroalbuminuria. Conclusion Our study revealed substantial deficiencies in the education of diabetic patients concerning foot care practices. The prevalent positive attitude among the patients indicates that diabetic foot disease can be effectively prevented with adequate patient education and proactive care by primary healthcare providers. Addressing these deficiencies in awareness and practice is essential for improving patient outcomes and preventing severe complications associated with diabetic foot disease.
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http://dx.doi.org/10.7759/cureus.85436 | DOI Listing |
Turkiye Parazitol Derg
September 2025
Fırat University Faculty of Fisheries, Department of Aquaculture and Fish Diseases, Elazığ, Türkiye.
Objective: Hirudotherapy (HT), the therapeutic use of medicinal leeches, has been practised for centuries, and the interest in modern medicine has recently been renewed. This study evaluates the clinical outcomes of HT at Herba Medical Center in Azerbaijan between 2020 and 2024, focusing on its efficacy across 11 medical conditions.
Methods: A total of 181 patients were treated using disposable medicinal leeches () sourced from hygienic farms approved by Azerbaijan's Ministry of Ecology and Natural Resources.
Foot Ankle Int
September 2025
Department of Orthopaedic Surgery and Rehabilitation and Department of Vascular and Endovascular Surgery, Atrium Health Wake Forest Baptist Medical Center, Wake Forest University School of Medicine, Winston-Salem, NC, USA.
Background: The Infectious Diseases Society of America guidelines recommend a prolonged course of antibiotics in the setting of residual osteomyelitis. More recently published literature suggests that oral antibiotics may offer comparable outcomes to intravenously administered antibiotics when treating orthopaedic infections. In a prior study, we investigated the outcomes of both routes of antibiotic administration in patients with diabetic foot infections at a single academic medical institution.
View Article and Find Full Text PDFSemin Vasc Surg
September 2025
Division of Vascular and Endovascular Surgery, Zucker School of Medicine at Hofstra/Northwell, Hempstead, NY; Comprehensive Wound Care Healing and Hyperbaric, Department of Surgery, Northwell Health System, 270-05 76(th) Avenue, New Hyde Park, NY 11040. Electronic address:
Nonhealing wounds are increasingly prevalent, present in 1% to 2% of the global population, with higher incidence in geriatric patients. These chronic wounds pose challenges to older adult patients owing to physiologic changes that hinder healing, common medical comorbidities that promote inflammation and damage microcirculation, poor nutritional status and mobility, and psychosocial barriers to receiving care. In this literature review, the epidemiology, pathophysiology, systems costs, and management of chronic venous leg ulcers, arterial ulcers, and diabetic foot wounds in older adult patients are investigated.
View Article and Find Full Text PDFPLoS One
September 2025
Department of Nephrology, Chungnam National University, Daejeon, Republic of Korea.
Diabetic kidney disease (DKD) involves oxidative stress-driven damage to glomeruli (Gloms) and proximal convoluted tubules (PCT). NAD(P)H: quinone oxidoreductase 1 (NQO1) regulates redox balance, but its compartment-specific role remains unclear. Streptozotocin (STZ)-induced hyperglycemia increased albuminuria and foot process effacement, with NQO1 KO (NKO) mice exhibiting greater podocyte injury than WT, indicating exacerbated glomerular damage.
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