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is a NASA Discovery-class mission to send a highly capable and robust spacecraft to investigate primitive bodies near both the L and L Lagrange points with Jupiter; the Jupiter Trojan asteroids. This heretofore unexplored population of planetesimals from the outer planetary system holds vital clues to deciphering the history of the Solar System. Due to an unusual and fortuitous orbital configuration, will perform a comprehensive investigation that visits eight Trojans, including all the recognized taxonomic classes, a collisional family member and a near equal-mass binary. It will visit objects with diameters ranging from roughly 1 to 100 km. In particular, will perform flybys of (3548) Eurybates and its satellite Queta (L, C-type), (15094) Polymele and its currently unnamed satellite (L, P-type), (11351) Leucus (L, D-type), (21900) Orus (L, D-type), and the (617) Patroclus-Menoetius binary (L, P-types). This diverse array of targets will supply invaluable constraints on the formation and early dynamical evolution of the giant planets. In addition, will visit two main-belt asteroids, (152830) Dinkinesh and (52246) Donaldjohanson, in order to practice its encounters. 's payload suite consists of a color camera and infrared imaging spectrometer, a high resolution panchromatic imager, and a thermal infrared spectrometer. Additionally, two spacecraft subsystems will also contribute to the science investigations: the terminal tracking cameras will supplement imaging during closest approach and the telecommunication subsystem will be used to measure the mass of the Trojans. launched on October 16, 2021 and will have encounters with the Trojans from August 2027 until March 2033.
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http://dx.doi.org/10.1007/s11214-025-01173-7 | DOI Listing |
Eur J Heart Fail
September 2025
Cardiology Department, University Medical Centre Ljubljana, Ljubljana, Slovenia.
Aims: There is a lack of data from randomized clinical trials comparing treatment outcomes between conduction system pacing (CSP) modalities and biventricular pacing (BVP) in symptomatic patients with refractory atrial fibrillation (AF) scheduled for atrioventricular node ablation (AVNA). The CONDUCT-AF investigates whether CSP is non-inferior to BVP in improving left ventricular ejection fraction (LVEF) and clinical outcomes in heart failure (HF) patients with symptomatic AF undergoing AVNA.
Methods: This study is an investigator-initiated, prospective, randomized, multicentre clinical trial conducted across 10 European centres, enrolling 82 patients with symptomatic AF, HF with reduced LVEF, and narrow QRS.
JMIR Res Protoc
September 2025
Department of Health Services Research & Administration, College of Public Health, University of Nebraska Medical Center, Omaha, NE, United States.
Background: With the availability of more advanced and effective treatments, life expectancy has improved among patients with metastatic breast cancer (MBC), but this makes communication with their medical oncologist more complex. Some patients struggle to learn about their therapeutic options and to understand and articulate their preferences. Mobile health (mHealth) apps can enhance patient-provider communication, playing a crucial role in the diagnosis, treatment, quality of life, and outcomes for patients living with MBC.
View Article and Find Full Text PDFJMIR Res Protoc
September 2025
Gender and Women's Health Unit, Nossal Institute for Global Health, School of Population and Global Health, The University of Melbourne, Carlton, Australia.
Background: Assisted vaginal birth is a lifesaving procedure where health workers use special devices to expedite birth vaginally when some complications emerge, such as due to prolonged labor. When the use of assisted vaginal birth is possible and appropriate, it provides benefits over cesarean section. These benefits include shorter recovery, reduced hospital stays, lower risks of complications, cost savings, and greater likelihood of vaginal birth in future pregnancies.
View Article and Find Full Text PDFJMIR Res Protoc
September 2025
Department of Food Science and Technology, Kaunas University of Technology, Kaunas, Lithuania.
Background: Fermented foods vary significantly by food substrate and regional consumption patterns. Although they are consumed worldwide, their intake and potential health benefits remain understudied. Europe, in particular, lacks specific consumption recommendations for most fermented foods.
View Article and Find Full Text PDFJMIR Res Protoc
September 2025
Center for Alcohol & Addiction Studies, School of Public Health, Brown University, Providence, RI, United States.
Background: Digital media frequently contains positive portrayals of alcohol content, which has been shown to be associated with alcohol-related cognitions and behaviors. Because youth are heavy media consumers and have access to unsupervised, repeat viewing of media content on their personal mobile devices, it is critical to understand the frequency of encountering alcohol content in adolescents' daily lives and how adolescents engage with the content.
Objective: This paper outlines the study protocol for examining adolescents' exposure to alcohol-related content in digital media within their natural environments.