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We describe the successful treatment of biliary duct obstruction (BDO) secondary to biliary carcinoma involving the bile duct, cystic duct, and intrahepatic ducts in two adult domestic shorthair cats using a novel technique. Both cats presented with marked hyperbilirubinemia, increased liver enzyme activities, and ultrasonographic evidence of BDO secondary to neoplasia. One cat previously had undergone cholecystoduodenostomy, with recurrence of BDO. Both cats were treated using a transhepatic biliary rendezvous procedure, in which a hybrid interventional radiological approach was used to place a self-expanding metallic stent into the left intrahepatic duct, into the common bile or cystic duct, and into the duodenum, relieving the obstruction. In both cases, BDO resolved at time of last follow-up. This technique offers an alternative to traditional surgical or interventional options for biliary decompression, particularly in cases of diffuse malignant biliary obstruction where access to the common bile duct (CBD) is challenging.
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http://dx.doi.org/10.1111/jvim.70178 | DOI Listing |
Int J Surg
September 2025
State Key Laboratory of Oncology in South China, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, China.
Introduction: Recent advancements in surgical techniques and perioperative care have improved cancer survival rates, yet postoperative comorbidity and mortality remain a critical concern. Despite progress in cancer control, systematic analyses of long-term mortality trends and competing risks in surgery-intervened cancer populations are lacking. This study aimed to quantify temporal patterns of postoperative mortality causes across 21 solid cancers and identify dominant non-cancer risk factors to inform survivorship care strategies.
View Article and Find Full Text PDFInt J Surg
September 2025
The Japanese Society of Gastroenterological Surgery, Tokyo, Japan.
Background: The association between preoperative liver function and short-term outcomes after gastrointestinal cancer surgery is unknown. This study investigated the impact of Child-Pugh score-based preoperative liver dysfunction on short-term outcomes after distal gastrectomy and right hemicolectomy.
Materials And Methods: We included patients who underwent distal gastrectomy for gastric cancer or right hemicolectomy for colon cancer between 2018 and 2022 from the Japanese National Clinical Database.
ACG Case Rep J
September 2025
Department of Gastroenterology and Hepatology, Henry Ford Hospital, Detroit, MI.
Biliary radiofrequency ablation is an emerging adjunctive and palliative therapy for patients with ampullary and biliary tumors. Given the high mortality for these malignancies, data on long-term complications are limited. We report a unique case of sphincterotomy restenosis causing biliary obstruction in a 98-year-old woman with a history of ampullary adenocarcinoma treated with papillectomy and biliary radiofrequency ablation (RFA).
View Article and Find Full Text PDFExp Clin Transplant
August 2025
>From the Department of Pediatric Hematology and Oncology, Baskent University Medical Faculty, Ankara, Turkey.
A 3-year-old female patient, who had received a liver transplant from her father 1 year previously to treat biliary atresia, was admitted with fever and pancytopenia. History showed Epstein-Barr virus polymerase chain reaction positivity detected in the patient 3 months earlier; the patient received reduced immunosuppression in doses of tacrolimus, and valganciclovir was administered. Physical exa-mination showed lymphadenopathies at the cervical, axillary and inguinal regions with 2 × 2 cm at diameter, splenomegaly of 5 cm, and fever of 39 °C.
View Article and Find Full Text PDFJAMA Netw Open
September 2025
Department of Internal Medicine, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, South Korea.
Importance: Patients with advanced cancer frequently receive broad-spectrum antibiotics, but changing use patterns across the end-of-life trajectory remain poorly understood.
Objective: To describe the patterns of broad-spectrum antibiotic use across defined end-of-life intervals in patients with advanced cancer.
Design, Setting, And Participants: This nationwide, population-based, retrospective cohort study used data from the South Korean National Health Insurance Service database to examine broad-spectrum antibiotic use among patients with advanced cancer who died between July 1, 2002, and December 31, 2021.