Aptamer-based biosensors for troponin detection.

Cardiac troponin is recognized as a valuable diagnostic for the early detection of acute myocardial infarction. Biosensors are great alternatives to electrocardiograms, chest X-rays, and other laboratory-based immunoassays because they can detect increased levels of cardiovascular protein biomarkers in the blood right after a myocardial infarction. They are also ideal for use as point-of-care platforms. Aptamers provide a compelling alternative to antibodies for analytical applications. Recently, aptamer-based biosensors, or aptasensors, have garnered significant attention for their ability to provide accessible and sensitive detection of cardiac troponin. This review presents a clear and concise overview of the recent advancements in various types of aptasensors, including fluorescence, surface plasmon resonance, colorimetric methods, surface-enhanced Raman scattering, electrochemical detection, and lateral flow assays, all developed for the determination of troponin.