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Objective: To explore the relationship between subfoveal choroidal thickness (SFCT) and persistent subretinal fluid (pSRF) at the macula after successful rhegmatogenous retinal detachment (RRD) surgery.
Methods: This is a retrospective multicenter comparative study of Caucasian subjects with successful RRD repair. SFCT was measured in 2 groups: Group 1 with persistent subretinal fluid (pSRF) 1 month after repair, and Group 2 with absence of pSRF. SFCT was measured by a masked observer based on ImageJ. Multiple regression analyses were implemented to control for age, refraction, and gender.
Results: Surgery type was as follows: Group 1 (24 scleral buckle SB, 23 pars plana vitrectomy PPV, 9 SB+PPV, and 5 pneumoretinopexy), and Group 2 (68 PPV). Adjusted mean 1-month SFCT was thicker in Group 1 than in Group 2 by 41.0 µm (p = 0.049). Within Group 1, PPV subgroup tended to have thinner SFCT than the other subgroups by: SB (117.4 µm), SB-PPV (9.3) and pneumoretinopexy (1.2 µm) (all p>0.05). SFCT at 1-month was not different between pSRF (237.5±77.2 µm) and no pSRF (213.7±72.1 µm) in PPV groups (p=0.2).
Conclusion: SFCT post PPV appeared similar in eyes with or without pSRF. In eyes with pSRF, SFCT tended to be thicker following SB compared to PPV.
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http://dx.doi.org/10.2147/OPTH.S520076 | DOI Listing |
Cureus
August 2025
Department of Ophthalmology, Tsurumi University School of Dental Medicine, Yokohama, JPN.
Traumatic vitreous hemorrhage is most commonly associated with sports injuries or accidental falls. We report an exceptionally rare case of vitreous hemorrhage presumed to result from blunt trauma inflicted by the forepaw of a domestic cat. A 50-year-old man presented with blurred vision and ocular pain in his right eye after being struck by his pet cat.
View Article and Find Full Text PDFInt Ophthalmol
August 2025
Hikichi Eye Clinic, Kita-7 Nishi-5 7-1 Kita-Sky-BuildingKita-ku, Sapporo, 060-0807, Japan.
Purpose: To evaluate longitudinal morphologic changes of the double-layer sign (DLS) on optical coherence tomography (OCT) in eyes with neovascular age-related macular degeneration (nAMD) presenting with exudative macular neovascularization (eMNV) undergoing anti-vascular endothelial growth factor (VEGF) therapy.
Methods: This retrospective study included 207 consecutive treatment-naïve eyes (207 patients) with nAMD presenting with eMNV and a DLS treated with intravitreal anti-VEGF injections and were followed for ≥ 12 months. All eyes received 3 monthly loading injections followed by either treat-and-extend (TAE) or pro re nata (PRN) retreatment, per predefined criteria.
Ophthalmic Surg Lasers Imaging Retina
August 2025
Pigmented epithelial detachment (PED) blowout in central serous chorioretinopathy (CSC) can present with intraretinal and subretinal fluid and hyperreflective foci, mimicking Type 3 macular neovascularization (MNV). Differentiating between pachychoroid neovasculopathy (PNV) and PED blowout is crucial for appropriate treatment. This report highlights the case of a 47-year-old male patient with chronic CSC and suspected PNV, experiencing persistent blurred vision despite nine intravitreal aflibercept 2 mg injections.
View Article and Find Full Text PDFGraefes Arch Clin Exp Ophthalmol
August 2025
Department of Ophthalmology, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-Ku, Fukuoka, 812-8582, Japan.
Purpose: This study aimed to assess the six-month outcomes of patients with pachychoroid neovasculopathy (PNV) treated with half-fluence photodynamic therapy (PDT) along with a single intravitreal aflibercept injection (IVA) and to identify factors linked to persistent or recurrent subretinal fluid (SRF).
Methods: This retrospective study included consecutive treatment-naïve PNV patients who received initial treatment with IVA and half-fluence PDT and were followed up for more than six months. Patient data, including sex, age, and baseline best-corrected visual acuity (BCVA), and imaging data, including optical coherence tomography (OCT), OCT angiography, and fundus autofluorescence (FAF), were retrospectively collected.
Ophthalmologie
August 2025
Augenzentrum am St. Franziskus-Hospital Münster, Hohenzollernring 74, 48145, Münster, Deutschland.
Background And Objective: Persistent central serous chorioretinopathy (CSC) is a complex macular disease that if left untreated can lead to deterioration of visual acuity and impairment of the quality of life. A treatment of choice is photodynamic therapy (PDT), which in studies has been shown to achieve stable functional and morphological results with a short follow-up period. As there are only few studies on the long-term evolution after PDT, this study aims to evaluate the long-term functional and morphological outcomes after PDT.
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