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Article Abstract
•Early aortic valve replacement before the development of severe symptomatic aortic stenosis is not associated with a benefit for most hard endpoints including mortality and myocardial infarction but is associated with a benefit in stroke.•The mechanism for the potential benefit of early aortic valve replacement on stroke remains unclear.•Younger patients and women may derive a mortality benefit from early aortic valve replacement, but this warrants further study.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC12207225 | PMC |
| http://dx.doi.org/10.1016/j.shj.2025.100461 | DOI Listing |
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