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Background: Implementing a full-sample prescription review system has become imperative for hospitals to address the limitations of post-review practices and ensure patient medication safety. In this study, we investigate the preliminary application impact of the prescription pre-review system (PPRS)and its rules maintenance in our hospital, while also evaluating the pharmaceutical service value resulting from the implementation of prescription pre-review.
Methods: We incorporated levels of prescribing warnings into the PPRS, while establishing and maintaining a database of appropriate medication practices. In addition, we evaluated the rationality of intravenous infusion prescriptions and key monitored drug prescriptions before and after the implementation of PPRS, and briefly evaluated the irrational prescriptions.
Results: A comprehensive range of 7 warning levels was established, reflective of the degree of prescription irrationality. Besides, a total of 3015 user rules were created to regulate medication behavior. The number and proportion of unreasonable prescriptions during January to March 2023 demonstrated a noteworthy reduction when compared to the corresponding period in 2022. Moreover, the continuous evaluation of systematic alert prescriptions during January to March 2023 indicated a remarkable monthly decline.
Conclusion: The introduction of the PPRS has ushered in a paradigm shift in the evaluation of prescription rationality. This transformative system has played a pivotal role in standardizing doctor’s prescribing patterns, thereby promoting the rational utilization of drugs in clinical practice. By ensuring patient safety, elevating the quality of care, and enhancing the value of pharmacists, the PPRS has emerged as a catalyst for positive change in the healthcare setting.
Supplementary Information: The online version contains supplementary material available at 10.1186/s12913-025-12901-8.
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http://dx.doi.org/10.1186/s12913-025-12901-8 | DOI Listing |
J Eval Clin Pract
August 2025
Department of Pharmacy, The Affiliated Yan'an Hospital of Kunming Medical University, Kunming, China.
Background: Prescription pre-review (PPR) is an important part of hospital pharmacy management, which aims to ensure the rationality, safety and effectiveness of prescriptions. However, due to the extensive and specialised nature of prescription review work, coupled with the high work intensity in hospitals, prescription errors occur from time to time, affecting the quality of medical care and patient safety.
Objective: Six Sigma DMAIC management method, as a systematic approach to improve service quality by reducing process variation and defects, was applied for the first time in the rectification practice of PPR work in our hospital.
BMC Health Serv Res
July 2025
Department of Pharmacy, The Affiliated Yan'an Hospital of Kunming Medical University, Kunming, China.
Background: Implementing a full-sample prescription review system has become imperative for hospitals to address the limitations of post-review practices and ensure patient medication safety. In this study, we investigate the preliminary application impact of the prescription pre-review system (PPRS)and its rules maintenance in our hospital, while also evaluating the pharmaceutical service value resulting from the implementation of prescription pre-review.
Methods: We incorporated levels of prescribing warnings into the PPRS, while establishing and maintaining a database of appropriate medication practices.
J Pharm Pract
June 2013
College of Pharmacy, University of Michigan, Ann Arbor, MI, USA.
The objective was to determine the impact of simulated pharmacist interventions on out-of-pocket cost, time to coverage gap, and cost per patient to the Medicare Part D program using actual patient cases from an adult general medicine clinic. Medication profiles of 100 randomly selected Medicare-eligible patients from a university-affiliated general internal medicine clinic were reviewed by a pharmacist to identify opportunities to cost-maximize the patients' therapies based on the plan. An online Part-D calculator, Aetna Medicare Rx Essentials, was used as the standard plan to determine medication cost and time to gap.
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