Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
The purpose of this study was to assess the retinal relative peripheral refraction (RPR) in children with low myopia and pre-myopia, and investigate the differences in RPR using multispectral refraction topography (MRT). Ninety-five children were enrolled in the Department of Ophthalmology, Jinshan Hospital affiliated to Fudan University. MRT could measure total RPR (TRPR) of the 53° range centered on macular fovea. TRPR divided into four quadrants: superior RPR (RPR-S), inferior RPR (RPR-I), temporal RPR (RPR-T) and nasal RPR (RPR-N). The MRT analysis report also showed RPR in the visual field of 15° (RPR-15), 30° (RPR-30) and 45° (RPR-45) centered on the macular fovea, respectively. RPR-(15-30), RPR-(30-45) and RPR-(15-45) were calculated. TRPR (R = - 0.264, P = 0.010), RPR-I (R = - 0.261, P = 0.011), RPR-T (R = - 0.240, P = 0.019), RPR-45 (R = - 0.211, P = 0.040), RPR-(30-45) (R = - 0.232, P = 0.023) and RPR-(15-45) (R = - 0.243, P = 0.018) were negatively correlated with spherical refraction. Spherical equivalent of low myopia group was significantly less than pre-myopia group (- 1.18 ± 0.57 D vs. 0.13 ± 0.31 D, P < 0.001) whereas axial length of low myopia group was significantly longer than pre-myopia group (24.14 ± 0.70 mm vs. 23.35 ± 0.60 mm, P < 0.001). TRPR of low myopia group and pre-myopia group was 0.52 ± 0.62 D and 0.32 ± 0.41 D, respectively, without sigficant difference (P = 0.075). All the RPRs were hyperopia in the children with low myopia and pre-myopia, except for RPR-T in pre-myopia group. RPR-I in low myopia group was significantly larger than that in pre-myopia group (0.42 ± 0.72 (95% CI 0.22, 0.62) D vs. 0.04 ± 0.67 (95% CI - 0.17, 0.25) D, P = 0.010). In conclusion, RPRs become more hyperopia with the changing trend from pre-myopia to myopia. Children with low myopia and pre-myopia have relative peripheral hyperopia. Furthermore, children with low myopia have larger relative peripheral hyperopia compared with pre-myopia.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC12216301 | PMC |
| http://dx.doi.org/10.1038/s41598-025-04334-4 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Investigation into the Therapeutic Efficacy and Inflammatory Modulatory Effects of the Combined Use of 0.01% Atropine Eye Drops and Orthokeratology Lenses in the Management of Myopia Among Adolescent Patients.
J Inflamm Res
September 2025
Department of Optometry, School of Health and Welfare, Dongshin University, Naju, Korea.
Objective: To evaluate the therapeutic efficacy and inflammatory modulatory effects of combined 0.01% atropine eye drops and orthokeratology (OK) lenses in controlling myopia progression among adolescent patients.
Methods: This retrospective study analyzed clinical data from 90 adolescent patients (90 eyes) with myopia treated from April 2021 to June 2023.
Response of accommodation and vergence systems to low dose atropine.
Ophthalmic Physiol Opt
September 2025
Centre for Vision and Eye Research, Queensland University of Technology, Brisbane, Queensland, Australia.
Purpose: Few studies have comprehensively investigated the effect of low dose atropine on the binocular vision system beyond accommodative amplitude. This study examined the effect of 0.05% atropine eye drops on a range of accommodation and vergence parameters across a 10-day period.
View Article and Find Full Text PDFThe role of inflammation in myopic retinopathy.
Front Ophthalmol (Lausanne)
August 2025
Aier Eye Institute, Changsha, China.
High myopia is a global health concern, often leading to degenerative retinal changes known as myopic retinopathy. Although mechanical stress, hypoperfusion, extracellular matrix remodeling, and growth factor dysregulation have been implicated in the pathogenesis of myopic retinopathy, emerging evidence highlights the critical role of chronic low-grade inflammation. Both innate and adaptive immune systems participate in myopic retinopathy through systemic and local inflammation.
View Article and Find Full Text PDFClinical features of high myopia with optic nerve head prelaminar schisis: Wuhan high myopia study.
Eye (Lond)
September 2025
Eye Center, Renmin Hospital of Wuhan University, Wuhan, China.
Background: The global prevalence of high myopia is rising, posing a significant public health concern. Limited research exists on risk factors for prelaminar schisis (PLS) and its impact on visual field changes in highly myopic eyes. Herein, we investigated clinical features of prelaminar schisis (PLS) in highly myopic eyes.
View Article and Find Full Text PDFRadiometric and safety assessment of a 'low-level red-light' myopia control device.
Ophthalmic Physiol Opt
September 2025
School of Optometry, Indiana University, Bloomington, Indiana, USA.
Purpose: Recent literature has demonstrated that 'low-level red-light therapy' may be effective at slowing axial elongation in children, but reports have questioned the safety of some red-light devices. The current work explored the beam characteristics and hazard potential for a myopia control red-light device.
Methods: The optical design and exiting beam characteristics of a sample red-light myopia control device (SECONEE sky-n1201a) were quantified by measuring beam divergence and total flux passing through artificial pupils of 1-9 mm diameter placed at the corneal plane.