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We report a generalized nonlinear Schrödinger equation simulation model of an extreme learning machine (ELM) based on optical fiber propagation. Using the MNIST handwritten digit dataset as a benchmark, we study how accuracy depends on propagation dynamics, as well as parameters governing spectral encoding, readout, and noise. For this dataset and with quantum noise limited input, test accuracies of over 91% and 93% are found for propagation in the anomalous and normal dispersion regimes, respectively. Our results also suggest that quantum noise on the input pulses introduces an intrinsic penalty to ELM performance.
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http://dx.doi.org/10.1364/OL.562186 | DOI Listing |
Brain Res Bull
September 2025
Department of Psychiatry, Keck School of Medicine, University of Southern California, Los Angeles, CA; Institute for the Developing Mind, Children's Hospital Los Angeles, Los Angeles, CA.
We propose a Biophysically Restrained Analog Integrated Neural Network (BRAINN), an analog electrical network that models the dynamics of brain function. The network interconnects analog electrical circuits that simulate two tightly coupled brain processes: (1) propagation of an action potential, and (2) regional cerebral blood flow in response to the metabolic demands of signal propagation. These two processes are modeled by two branches of an electrical circuit comprising a resistor, a capacitor, and an inductor.
View Article and Find Full Text PDFVirology
September 2025
Department of Microbiology, Faculty of Pharmacy, Ahram Canadian University (ACU), 6th October City, Giza, 12566, Egypt. Electronic address:
Background: Carbapenem-resistant Acinetobacter baumannii (CRAB) has recently become a serious cause for global concern because of non-susceptibility to multiple antimicrobial classes, its prevalence in nosocomial infections, and the lack of effective treatments against such a pathogen.
Methods: This study isolated two lytic phages from hospital sewage, purified, propagated, characterized morphologically by transmission electron microscopy, and genomically by Oxford Nanopore Sequencing. The phage lysates were then formulated individually as carboxymethylcellulose (CMC) 5 % w/v hydrogels.
Clin Neurophysiol
August 2025
University of Queensland, Centre for Clinical Research, Herston, QLD, Australia; Royal Brisbane & Women's Hospital, Herston, QLD, Australia. Electronic address:
Objective: High-density surface electromyography (HD-sEMG) is a non-invasive and quantitative tool for studying neuromuscular disorders, enabling assessments of muscle excitation, motor unit (MU) characteristics and firing patterns. This systematic review reports the published evidence on the clinical applications of HD-sEMG across neuromuscular disorders, identifying the range of disorders studied, indexes utilized, and gaps in the literature.
Methods: Systematic searches in PubMed and Scopus identified 200 studies, of which 55 met the inclusion criteria.
Front Immunol
September 2025
Department of Pharmacy, Shenzhen Longhua District Central Hospital, Shenzhen, China.
The immune interactions within the gut-brain axis represent a critical etiological factor in psychiatric disorders. The gut microbiota and their metabolites serve as biological mediators that regulate neuroimmune activation and suppression in the central nervous system (CNS). During intestinal immune activation, pro-inflammatory cytokines (, IL-6, TNF-α) propagate to the CNS compromised blood-brain barrier (BBB) integrity or vagal afferent fibers, disrupting neurotransmitter metabolism and inducing microglial hyperactivation, thereby exacerbating neuroinflammation.
View Article and Find Full Text PDFInd Eng Chem Res
August 2025
School of Chemical and Biomolecular Engineering, Georgia Institute of Technology, Atlanta, Georgia 30332, United States.
Pervaporation, combined with other separation processes, can effectively remove water from fermentation product streams, making it highly suitable for purifying alcohols like 2,3-butanediol (BDO). In this study, a dense poly-(vinylidene fluoride) (PVDF) hollow fiber membrane module prototype was fabricated for BDO dehydration, achieving >0.2 LMH total flux and >95% BDO rejection.
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