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Article Abstract
Introduction: Crohn's disease (CD) and ulcerative colitis (UC) are characterized by persistent gastrointestinal inflammation. Timely, effective management is crucial for improving long-term patient outcomes.
Materials And Methods: As part of the IBD-PODCAST study, this cross-sectional, multicenter, non-interventional study included 396 patients (196 CD, 200 UC) from 14 Spanish hospitals, aiming to assess treat-to-target implementation through monitoring practices in a real-world setting. Biochemical markers (CRP, fCal) measured within ±14 days of index date and imaging tests (endoscopy, IUS, MRI/MRE/CT) during the previous year were collected. Actions taken based on the results were evaluated.
Results: Biochemical markers were requested in more than half the patients and imaging in a third, including endoscopic procedures in 18.9% of CD and 28% of UC cases, and IUS in <12% of patients. Treatment was adjusted in 67% of CD patients with symptoms and 67% of UC patients with rectal bleeding. Only 39% of CD and 26% of UC patients with abnormal fCal had treatment modifications, with 35% and 37% undergoing additional monitoring, respectively. Endoscopic findings prompted adjustments in 87% of CD and 56% of UC patients.
Conclusion: The IBD-PODCAST study examines routine IBD management in Spain, highlighting the need for improved monitoring and intervention to optimize patient care and outcomes.
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| http://dx.doi.org/10.17235/reed.2025.11190/2025 | DOI Listing |
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Introduction: Crohn's disease (CD) and ulcerative colitis (UC) are characterized by persistent gastrointestinal inflammation. Timely, effective management is crucial for improving long-term patient outcomes.
Materials And Methods: As part of the IBD-PODCAST study, this cross-sectional, multicenter, non-interventional study included 396 patients (196 CD, 200 UC) from 14 Spanish hospitals, aiming to assess treat-to-target implementation through monitoring practices in a real-world setting.
IBD impact on quality of life and perception of disease activity in Italian patients and physicians: An IBD-PODCAST study sub analysis.
Dig Liver Dis
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Gastroenterology and Endoscopy, IRCCS Ospedale San Raffaele and University Vita-Salute San Raffaele Milano, Milan, Italy.
Background: IBD-PODCAST was a global real-world study to assess suboptimal disease control (SDC) in patients with Crohn's disease (CD) and ulcerative colitis (UC) using STRIDE-II criteria.
Aim: To evaluate quality of life (QoL), disease characteristics and control in patients with SDC, comparing perspectives of patients and healthcare providers (HCPs) in the Italian subpopulation.
Methods: IBD-PODCAST-Italy enrolled adult outpatients from 17 centers.
Assessing disease control in inflammatory bowel disease: a real world cross-sectional study in the UK (PODCAST-IBD).
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Department of Inflammatory Bowel Disease, St Mark's Hospital, The National Bowel Hospital, London, UK.
Article Synopsis
- - The PODCAST-IBD study aimed to evaluate disease control in IBD patients according to STRIDE-II guidelines, assessing data from 198 individuals in UK clinics from October 2022 to January 2023.
- - Results showed that over half of the patients with Crohn's disease (52.4%) and ulcerative colitis (45.3%) experienced suboptimal disease control, largely due to impaired quality of life, which also affected fatigue and disability levels.
- - The study highlighted significant economic burdens, revealing that suboptimal disease control led to over twice the healthcare costs and increased work productivity losses, suggesting regular quality of life assessments could enhance disease monitoring and treatment efficacy.
Suboptimal disease control and contributing factors in Italian IBD patients: The IBD-PODCAST Study.
Dig Liver Dis
January 2025
Gastroenterology and Endoscopy, IRCCS Ospedale San Raffaele and University Vita-Salute San Raffaele Milano, Milan, Italy.
Background And Aim: Suboptimal disease control (SDC) and its contributing factors in IBD according to STRIDE-II criteria is unclear. IBD-PODCAST was a non-interventional, international, multicenter real-world study to assess this.
Methods: Data from the Italian IBD cohort (N=220) are presented here.
Proportion of inflammatory bowel diseases patients with suboptimal disease control in daily clinical practice-Real-world evidence from the inflammatory bowel diseases-podcast study.
United European Gastroenterol J
July 2024
Department of Medicine I, Agaplesion Markus Hospital, Goethe University, Frankfurt am Main, Germany.
Background: Crohn's disease and ulcerative colitis (UC) are inflammatory bowel diseases (IBD) characterized by a progressive nature of the disease resulting in subsequent intestinal damage, limited efficacy of current treatments and suboptimal disease management and a significant burden for patients.
Objectives: The IBD-PODCAST study aims to estimate the proportion of Crohn's disease and UC patients with suboptimal disease control (SDC) in a real-world setting.
Methods: A non-interventional and cross-sectional study was conducted across 103 sites in 10 countries (Austria, Belgium, Canada, Germany, Greece, Italy, Portugal, Spain, Turkey, and UK).