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This study explores the impact of thermal annealing on the magnetic signal enhancement of three distinct Metglas ribbon materials: 2826MB3, 2605SA1, and 2714A. Each material underwent a systematic annealing process under a range of temperatures (50-500 °C) and durations (10-60 min) to evaluate the influence of thermal treatment on their magnetic signal response. The experimental setup applied a constant excitation frequency of 20 kHz, allowing for direct comparison under identical measurement conditions. The results show that while all three alloys benefit from annealing, their responses differ in magnitude, stability, and sensitivity. The 2826MB3 and 2605SA1 ribbons exhibited similar enhancement patterns, with maximum normalized voltage increases of 75.8% and approximately 70%, respectively. However, 2605SA1 displayed a more abrupt signal drop at elevated temperatures, suggesting reduced thermal stability. In contrast, 2714A reached the highest enhancement at 86.8% but also demonstrated extreme sensitivity to over-annealing, losing its magnetic response rapidly at higher temperatures. The findings highlight the critical role of carefully optimized annealing parameters in maximizing sensor performance and offer practical guidance for the development of advanced magnetoelastic sensing systems.
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http://dx.doi.org/10.3390/s25123722 | DOI Listing |
Brain Res Bull
September 2025
Department of Psychiatry, Keck School of Medicine, University of Southern California, Los Angeles, CA; Institute for the Developing Mind, Children's Hospital Los Angeles, Los Angeles, CA.
We propose a Biophysically Restrained Analog Integrated Neural Network (BRAINN), an analog electrical network that models the dynamics of brain function. The network interconnects analog electrical circuits that simulate two tightly coupled brain processes: (1) propagation of an action potential, and (2) regional cerebral blood flow in response to the metabolic demands of signal propagation. These two processes are modeled by two branches of an electrical circuit comprising a resistor, a capacitor, and an inductor.
View Article and Find Full Text PDFJ Control Release
September 2025
School of Biomedical Engineering, Shenzhen Campus of Sun Yat-sen University, Shenzhen 518107, Guangdong, China; Dongguan Liaobu Hospital, Dongguan 523400, Guangdong, China. Electronic address:
Fluorine-19 magnetic resonance imaging (F MRI) offers distinct advantages, including background-free signal detection, quantitative analysis, and deep tissue penetration. However, its application is currently limited by challenges associated with existing F MRI contrast agents, such as short transverse relaxation times (T), limited imaging sensitivity, and suboptimal biocompatibility. To overcome these limitations, a glutathione (GSH)-responsive triblock copolymer (PB7), featuring self-immolative characteristics, has been developed.
View Article and Find Full Text PDFPhys Med Biol
September 2025
Institute of Applied Medical Engineering, Helmholtz Institute, RWTH Aachen University Medical Faculty, Pauwelsstraße 20, Aachen, 52074, GERMANY.
Objective: Magnetic particle imaging (MPI) opens huge possibilities in image-guided therapy. Its effectiveness is strongly influenced by the quality of the magnetic nanoparticles (MNP) used as tracers. Besides MNP optimization following different synthesis routes, MNP assembly into linear structures can significantly enhance their performance in MPI.
View Article and Find Full Text PDFBiosens Bioelectron
September 2025
College of Pharmacy, Xinjiang Key Laboratory of Biopharmaceuticals and Medical Devices, Xinjiang Medical University, Urumqi, 830017, China; State Key Laboratory Basis of Xinjiang Indigenous Medicinal Plants Resource Utilization, Xinjiang Technical Institute of Physics and Chemistry, Chinese Academy
Given the pivotal role of Flap endonuclease 1 (FEN1) in tumor pathogenesis and progression, the advancement of its activity and inhibitor assays holds significant importance for cancer research and drug screening. Herein, we proposed a convenient, visual and sensitive colorimetric biosensing platform for FEN1 activity detection by integrating the robust signal amplification power of rolling circle amplification (RCA), the target enrichment capability of magnetic beads (MB), and the high efficiency and visualization of urease-mediated litmus test. Based on the significant color transition with a clear response mechanism, quantitative analysis can be achieved by either spectroscopic or smartphone-based detection.
View Article and Find Full Text PDFPhys Rev Lett
August 2025
University of Texas at Austin, Department of Physics, Austin, Texas 78712, USA.
We show that the ground state of a weakly charged two-dimensional electron-hole fluid in a strong magnetic field is a broken translation symmetry state with interpenetrating lattices of localized vortices and antivortices in the electron-hole-pair field. The vortices and antivortices carry fractional charges of equal sign but unequal magnitude and have a honeycomb-lattice structure that contrasts with the triangular lattices of superconducting electron-electron-pair vortex lattices. We predict that increasing charge density or a weakening magnetic field drives a vortex delocalization transition that would be signaled experimentally by an abrupt increase in counterflow transport resistance.
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