Understanding neurogenic urogenital dysfunction and the clinical application of the EAN/EFAS/INUS NEUROGED guidelines.

Auton Neurosci

Department of Neurology, Referral Center for the Demyelinating Diseases of the Central Nervous System and Referral Center for the Autonomic Nervous System Disorders, University Hospital Center Zagreb and University of Zagreb, School of Medicine, Zagreb, Croatia; University of Zagreb, School of Medic

Published: August 2025


Category Ranking

98%

Total Visits

921

Avg Visit Duration

2 minutes

Citations

20

Article Abstract

Neurogenic urogenital dysfunction encompasses various urinary and sexual issues resulting from neurological disorders, which significantly impact patients' quality of life. To address these challenges, the European Academy of Neurology (EAN), in collaboration with the European Federation of Autonomic Societies (EFAS) and the International Neuro-Urology Society (INUS), developed the NEUROGED guidelines. These guidelines aim to provide neurologists with evidence-based recommendations for managing neurogenic bladder and sexual dysfunctions. The task force comprised 37 members from 17 countries across four continents, highlighting a comprehensive and collaborative effort. The committee has established evidence-based recommendations for 11 key questions, consensus-based recommendations for eight questions, and good practice statements for 19, addressing the complexities of managing neurogenic urogenital dysfunction. This review seeks to enhance understanding of the NEUROGED guidelines through two sections. The first section examines the neuroanatomy, pathophysiology, and clinical presentation of lower urinary tract symptoms (LUTS) and sexual dysfunction (SD), establishing a basis for the guidelines. The second section explores the impact of the NEUROGED guidelines on the investigation and management of urogenital symptoms, addressing their implementation and potential barriers in clinical practice.

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.autneu.2025.103314DOI Listing

Publication Analysis

Top Keywords

neuroged guidelines
16
neurogenic urogenital
12
urogenital dysfunction
12
evidence-based recommendations
8
managing neurogenic
8
guidelines
6
understanding neurogenic
4
urogenital
4
dysfunction
4
dysfunction clinical
4

Similar Publications

Understanding neurogenic urogenital dysfunction and the clinical application of the EAN/EFAS/INUS NEUROGED guidelines.

Auton Neurosci

August 2025

Department of Neurology, Referral Center for the Demyelinating Diseases of the Central Nervous System and Referral Center for the Autonomic Nervous System Disorders, University Hospital Center Zagreb and University of Zagreb, School of Medicine, Zagreb, Croatia; University of Zagreb, School of Medic

Neurogenic urogenital dysfunction encompasses various urinary and sexual issues resulting from neurological disorders, which significantly impact patients' quality of life. To address these challenges, the European Academy of Neurology (EAN), in collaboration with the European Federation of Autonomic Societies (EFAS) and the International Neuro-Urology Society (INUS), developed the NEUROGED guidelines. These guidelines aim to provide neurologists with evidence-based recommendations for managing neurogenic bladder and sexual dysfunctions.

View Article and Find Full Text PDF

Background: Urinary and sexual symptoms are common following neurological disease, and we aimed to develop multidisciplinary inter-society evidence-based management guidelines.

Methods: The ADAPTE framework was used, and a systematic search of guidelines published in different languages was performed. Guidelines, consensus statements, and systematic reviews were included, and guideline quality was appraised using AGREE II.

View Article and Find Full Text PDF