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Neurogenic urogenital dysfunction encompasses various urinary and sexual issues resulting from neurological disorders, which significantly impact patients' quality of life. To address these challenges, the European Academy of Neurology (EAN), in collaboration with the European Federation of Autonomic Societies (EFAS) and the International Neuro-Urology Society (INUS), developed the NEUROGED guidelines. These guidelines aim to provide neurologists with evidence-based recommendations for managing neurogenic bladder and sexual dysfunctions. The task force comprised 37 members from 17 countries across four continents, highlighting a comprehensive and collaborative effort. The committee has established evidence-based recommendations for 11 key questions, consensus-based recommendations for eight questions, and good practice statements for 19, addressing the complexities of managing neurogenic urogenital dysfunction. This review seeks to enhance understanding of the NEUROGED guidelines through two sections. The first section examines the neuroanatomy, pathophysiology, and clinical presentation of lower urinary tract symptoms (LUTS) and sexual dysfunction (SD), establishing a basis for the guidelines. The second section explores the impact of the NEUROGED guidelines on the investigation and management of urogenital symptoms, addressing their implementation and potential barriers in clinical practice.
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http://dx.doi.org/10.1016/j.autneu.2025.103314 | DOI Listing |
Auton Neurosci
August 2025
Department of Neurology, Referral Center for the Demyelinating Diseases of the Central Nervous System and Referral Center for the Autonomic Nervous System Disorders, University Hospital Center Zagreb and University of Zagreb, School of Medicine, Zagreb, Croatia; University of Zagreb, School of Medic
Neurogenic urogenital dysfunction encompasses various urinary and sexual issues resulting from neurological disorders, which significantly impact patients' quality of life. To address these challenges, the European Academy of Neurology (EAN), in collaboration with the European Federation of Autonomic Societies (EFAS) and the International Neuro-Urology Society (INUS), developed the NEUROGED guidelines. These guidelines aim to provide neurologists with evidence-based recommendations for managing neurogenic bladder and sexual dysfunctions.
View Article and Find Full Text PDFEur J Neurol
April 2025
Department of Neurology, Referral Center for the Demyelinating Diseases of the Central Nervous System and Referral Center for the Autonomic Nervous System Disorders, University Hospital Center Zagreb, Zagreb, Croatia.
Background: Urinary and sexual symptoms are common following neurological disease, and we aimed to develop multidisciplinary inter-society evidence-based management guidelines.
Methods: The ADAPTE framework was used, and a systematic search of guidelines published in different languages was performed. Guidelines, consensus statements, and systematic reviews were included, and guideline quality was appraised using AGREE II.