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As per a WHO survey conducted in 2023, more than 2.3 million breast cancer (BC) cases are reported every year. In nearly 95% of countries, the second leading cause of death for females is BC. Breast and cervical cancers cause 80% of reported deaths in middle-income countries. Early detection of breast cancer can help patients better manage their condition and increase their chances of survival. However, traditional AI models frequently conceal their decision-making processes and are mainly tailored for classification tasks. Our approach combines composite deep learning techniques with explainable artificial intelligence (XAI) to enhance interpretability and predictive accuracy. By utilizing XAI to examine features and provide insights into its classifications, the model clarifies the rationale behind its decisions, resulting in an understanding of concealed patterns linked to breast cancer detection. The XAI strengthens practitioners' and health researchers' confidence and understanding of artificial intelligence (AI)-based models. In this work, we introduce a hybrid deep learning bi-directional long short-term memory-convolutional neural network (BiLSTM-CNN) model to identify breast cancer using patient data effectively. We first balanced the dataset before using the BiLSTM-CNN model. The hybrid deep learning (DL) model presented here performed well in comparison to other studies, with 0.993 accuracy, precision 0.99, recall 0.99, and F1-score 0.99.
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http://dx.doi.org/10.7717/peerj-cs.2806 | DOI Listing |
JMIR Res Protoc
September 2025
Department of Health Services Research & Administration, College of Public Health, University of Nebraska Medical Center, Omaha, NE, United States.
Background: With the availability of more advanced and effective treatments, life expectancy has improved among patients with metastatic breast cancer (MBC), but this makes communication with their medical oncologist more complex. Some patients struggle to learn about their therapeutic options and to understand and articulate their preferences. Mobile health (mHealth) apps can enhance patient-provider communication, playing a crucial role in the diagnosis, treatment, quality of life, and outcomes for patients living with MBC.
View Article and Find Full Text PDFCancer Epidemiol Biomarkers Prev
September 2025
Kangbuk Samsung Hospital, Seoul, Korea (South), Republic of.
Background: Iron metabolism may influence breast cancer development; however, links between iron-related biomarkers and breast cancer remain inconclusive. Given differences in iron status by menopausal status, we examined associations of ferritin and other iron biomarkers, with breast cancer incidence, stratified by menopausal status, in a Korean screening cohort.
Methods: This cohort study included 140,747 Korean women screened for breast cancer from 2011-2020.
Cancer Epidemiol Biomarkers Prev
September 2025
National Cancer Institute, Bethesda, MD, United States.
Background: Alcohol consumption is a risk factor for certain cancers and is increasing in the United States. We estimated the impact of alcohol consumption on cancer incidence trends in the United States from 2008-2019 across six alcohol-related cancers among men and women.
Methods: Average daily alcohol consumption (ADC) was calculated from the National Health Interview Survey (NHIS, 1998-2009) and adjusted to per capita sales data to account for underreporting alcohol use.
Cell Mol Biol (Noisy-le-grand)
September 2025
Assistant Professor of General Surgery, Department of Surgery, College of Medicine, University of Duhok, Kurdistan Region, Iraq.
Hormonal status and lymphatic invasion are two important prognostic factors among cases of breast cancer. This study aims to assess and evaluate the hormonal receptor status and lymph node involvement among female breast cancer patients in Duhok city, Kurdistan region, Iraq. A retrospective cross-sectional study was conducted, involving 156 diagnosed cases of breast cancer who had undergone surgical treatment and laboratory investigations at Azadi Teaching Hospital and Duhok Private Hospital for 30 months.
View Article and Find Full Text PDFRadiol Med
September 2025
Breast Imaging Division, Radiology Department, IEO European Institute of Oncology IRCCS, 20141, Milan, Italy.
Metastatic involvement (MB) of the breast from extramammary malignancies is rare, with an incidence of 0.09-1.3% of all breast malignancies.
View Article and Find Full Text PDF