Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
We estimated the serial interval and superspreading potential to quantify pertussis transmission dynamics in a 2024 school-based outbreak of a population in South Korea that had received a series of pertussis vaccinations. We analyzed 48 cases of pertussis and reconstructed 36 transmission pairs. We then used maximum-likelihood estimation to assess serial interval and offspring distribution from transmission pair data. We identified that the mean serial interval was 9.5 (SD 1.6) days; 15% (95% CI 8%-23%) of cases seeded 80% of all transmissions in this outbreak. Our findings suggest that pertussis was highly transmissible in vaccinated children during this outbreak. Rapid contact tracing and strict adherence to public health measures are needed to reduce community pertussis transmission.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC12205447 | PMC |
| http://dx.doi.org/10.3201/eid3107.241643 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Metastasis-directed radiotherapy without systemic therapy for oligometastatic clear-cell renal-cell carcinoma: primary efficacy analysis of a single-arm, single-centre, phase 2 trial.
Lancet Oncol
September 2025
Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA; Department of Genitourinary Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Background: Select patients with metastatic clear-cell renal-cell carcinoma can be treated without systemic therapy, yet few studies have explored this population. We investigated the efficacy of metastasis-directed therapy without systemic therapy in oligometastatic clear-cell renal-cell carincoma.
Methods: This investigator-initiated single-arm, phase 2 trial enrolled patients aged 18 years or older with an Eastern Cooperative Oncology Group performance status of 0-2, histologically confirmed clear-cell renal-cell carcinoma, and one to five metastases.
The prognostic values of monitoring changes in coagulative, inflammatory, and blood chemistry markers in COVID-19 patient's before and during admission to ICU: a retrospective cohort study.
Ann Med Surg (Lond)
September 2025
Sheikh Khalifa Medical City, Ajman, United Arab Emirates.
Introduction: The infection caused by the COVID-19 virus is associated with thromboembolic events and severe inflammatory reactions, significantly impacting the prognosis of infected patients. Numerous studies have indicated that COVID-19 patients often exhibit a hypercoagulable state, disseminated intravascular coagulation, and overwhelming inflammation, particularly in critically ill patients with multiple comorbidities requiring admission to the ICU. This study aims to assess the prognostic significance of alterations in coagulation, inflammatory, and blood chemistry markers in COVID-19 patients both before and during admission to the ICU.
View Article and Find Full Text PDFDeep learning mammography-based breast cancer risk model, its serial change, and breast cancer mortality.
Breast Cancer
September 2025
Center for Cohort Studies, Total Healthcare Center, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, South Korea.
Background: Although numerous breast cancer risk prediction models have been developed to categorize individuals by risk, a substantial gap persists in evaluating how well these models predict actual mortality outcomes. This study aimed to investigate the association between Mirai, a deep learning model for risk prediction based on mammography, and breast cancer-specific mortality in a large cohort of Korean women.
Methods: This retrospective cohort study examined 124,653 cancer-free women aged ≥ 34 years who underwent mammography screening between 2009-2020.
Effects of Sedation on Rectal Temperature During Equine Dental Procedures Performed in Cold to Warm Ambient Temperatures.
J Vet Dent
September 2025
Large Animal Clinical Sciences, Michigan State University College of Veterinary Medicine, East Lansing, MI, USA.
Sedation is important for safe equine dental procedures, but it is unknown if there is a higher risk of sedation causing hypothermia in procedures performed during cold months. The authors hypothesize that sedation for a dental procedure will significantly decrease rectal body temperature in cold as compared to warm ambient temperatures. Adult equids ( = 246), from a private equine dentistry practice, that underwent dental equilibration, were selected for the study.
View Article and Find Full Text PDFProteomic Biomarkers Are Linked to QTc Interval in Patients With Chronic Heart Failure.
Proteomics Clin Appl
September 2025
Department of Cardiology, Thorax Center, Cardiovascular Institute, Erasmus MC, Rotterdam, the Netherlands.
Objective: This study investigates the link between circulating proteins and rate-corrected QT (QTc) interval in patients with heart failure with reduced ejection fraction (HFrEF) and their association with cardiovascular outcomes.
Methods And Results: We analyzed 197 HFrEF patients from the prospective Serial Biomarker Measurements and New Echocardiographic Techniques in Chronic Heart Failure Patients Result in Tailored Prediction of Prognosis (Bio-SHiFT) study, all in sinus rhythm at baseline. Baseline QTc intervals were calculated and corrected for broad QRS complexes (>120 ms) using Bogossian's formula.