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http://dx.doi.org/10.1002/adma.202511074 | DOI Listing |
Dent Mater
September 2025
Faculty of Dentistry, National University of Singapore, Singapore; ORCHIDS: Oral Care Health Innovations and Designs Singapore, National University of Singapore, Singapore. Electronic address:
Objectives: To develop and validate predictive machine learning model capable of estimating long-term pH profiles (up to 672 h) of calcium silicate-based cements (CSCs) using early-stage pH measurements (3 and 24 h).
Materials And Methods: pH and calcium ion release data from in vitro studies (2014 - 2024) were extracted and analysed using descriptive statistics and correlation metrics. Feature selection was conducted using Random Forest regressors to identify key variables.
Antioxidants (Basel)
July 2025
Department of Food and Drug, University of Parma, Viale Parco Area delle Scienze 27/A, 43124 Parma, Italy.
In the original publication [...
View Article and Find Full Text PDFJ Ethnopharmacol
August 2025
Division of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, The Ohio State University, Columbus, OH, 43210, USA. Electronic address:
Ethnopharmacological Relevance: Correct taxonomic identification and depositing voucher herbarium specimens in an internationally recognized herbarium institution listed in the Index Herbariorum (https://sweetgum.nybg.org/science/ih/), such as the John G.
View Article and Find Full Text PDFEur J Pharmacol
August 2025
Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100193, China; Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicines, Ministry of Education, Beijing, 100193, China; Beijing Key Laboratory of
Cerebral ischemia/reperfusion injury (CIRI) poses a significant threat to human life and health. Ginsenoside Rb3 (Rb3) is known to exhibit protective effects against myocardial ischemia, its impact on CIRI remains unclear. Therefore, we investigated the protective effects of Rb3 on CIRI and its underlying mechanisms.
View Article and Find Full Text PDFJ Ethnopharmacol
August 2025
Cell Therapy & Cell Drugs Key Laboratory of Luzhou, Department of Pharmacology, School of Pharmacy, Southwest Medical University, 646000, Luzhou, Sichuan, China; South Sichuan Institute of Translation Medicine, 646000, Luzhou, Sichuan, China. Electronic address:
Ethnopharmacological Relevance: Alcoholic liver disease (ALD), a chronic liver injury induced by prolonged alcohol consumption, involves intricate multi-organ interactions, such as gut-liver axis disruption, as well as the synergistic effects of multiple factors including oxidative stress, intestinal dysbiosis, and metabolic disturbances. These complex pathological mechanisms render single-target therapies largely ineffective in achieving desirable therapeutic outcomes. Traditional Chinese medicine (TCM), characterized by its multi-target mechanisms and low toxicity, has demonstrated unique advantages in the treatment of ALD in the past decades.
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