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http://dx.doi.org/10.1136/gutjnl-2025-336129 | DOI Listing |
J Clin Epidemiol
September 2025
Australian Living Evidence Collaboration, School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC, Australia.
Objectives: Guideline developers have long recognised the importance of maintaining up-to-date guidelines to support evidence-based practice and policy, contributing to narrowing the gap between research generation and its application. This commentary reflects on key insights from the Journal of Clinical Epidemiology's Methods for Living Guidelines series and issues an open call for contributions aimed at advancing the development, implementation and evaluation of living guideline methods.
Methods: This commentary synthesises methodological innovations and practice experiences shared in the Methods for Living Guidelines series, highlighting emerging practices and lessons learned.
BMJ Open
August 2025
Health Services Research and Policy, London School of Hygiene & Tropical Medicine, London, UK.
Objectives: This study compares the implementation of C-reactive Protein (CRP) testing to distinguish between acute bacterial and viral infections in primary care in three WHO European region countries (Sweden, the Netherlands and the UK) and one WHO Americas region country (Canada) to generate insights that health services can use to guide decision-making on CRP test implementation.
Setting: Three settings were included: (1) national-level policy interviewees in England, (2) front-line antibiotic prescribers operating in primary care in England and (3) national-level policy interviewees in Canada, Sweden and the Netherlands.
Participants: We conducted in-depth qualitative interviews with 35 UK antimicrobial resistance policy-makers, clinicians and allied medical professionals.
NeuroRehabilitation
August 2025
Department of Physical Medicine and Rehabilitation, College of Medicine, University of Saskatchewan, Saskatoon, SK, Canada.
BackgroundEvidence to guide multiple sclerosis (MS) rehabilitation and symptomatic care has grown, yet suboptimal access to care persists and uptake of evidence-based information is limited in practice. The movement of evidence into routine clinical care is not a spontaneous or linear process. Effective knowledge mobilization strategies may enhance equitable access to evidenced-based comprehensive MS care.
View Article and Find Full Text PDFBMJ Open
August 2025
School of Psychology, Women's Health Research Wales, Cardiff University, Cardiff, UK.
Introduction: Sharing bad news (SBN) is a recurring and stressful challenge for fertility staff and patients. Suboptimal SBN is associated with staff burnout, patient dissatisfaction with care and lack of trust in staff, potentially leading to patient discontinuation. Patients value staff having SBN skills, but staff feel unprepared to do this task.
View Article and Find Full Text PDFCureus
July 2025
Infectious Disease, BuAliSina Hospital, Qazvin, IRN.
Introduction Antimicrobial resistance (AMR) is a pressing global health issue, exacerbated by inappropriate antibiotic use. In Iran, the 2016 National Action Plan on AMR established hospital-based antimicrobial stewardship programs (ASPs), including audit-feedback, prescription restrictions, and guideline-based prescribing to promote rational prescribing. The COVID-19 pandemic disrupted these efforts, resulting in increased empirical antibiotic use.
View Article and Find Full Text PDF