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http://dx.doi.org/10.6009/jjrt.25-0604 | DOI Listing |
Br J Haematol
September 2025
Nuffield Department of Population Health, University of Oxford, Oxford, UK.
When a new phenomenon is reported, despite many previous reports on larger cohorts of patients, one naturally asks why the finding is novel. Is this a new phenomenon, or merely identified because one is looking carefully for it for the first time? This commentary explores possible reasons for the novel finding of essential thrombocytopenia emerging in a cohort of Nucleophosmin 1 (NPM1)-mutated acute myeloid leukaemia (AML) patients. Commentary on: Bertoli et al.
View Article and Find Full Text PDFBiosens Bioelectron
August 2025
State Key Laboratory of Frigid Zone Cardiovascular Diseases (SKLFZCD), College of Pharmacy, Harbin Medical University, Heilongjiang, 150081, China; Research Unit of Health Sciences and Technology (HST), Faculty of Medicine University of Oulu, Finland; Heilongjiang Eye Hospital, Harbin, 150001, China
SERS has revolutionized viral detection with its high sensitivity and specificity. This review comprehensively explores the application progress, challenges, and future directions of SERS in viral detection. Firstly, the fundamental principles of SERS are introduced.
View Article and Find Full Text PDFCrit Rev Anal Chem
September 2025
Department of Pharmaceutical Chemistry, JSS College of Pharmacy, JSS Academy of Higher Education & Research, Mysore, India.
The miniaturization of separation platforms marks a transformative shift in analytical science, merging microfabrication, automation, and intelligent data integration to meet rising demands for portability, sustainability, and precision. This review critically synthesizes recent technological advances reshaping the field-from microinjection and preconcentration modules to compact, high-sensitivity detection systems including ultraviolet-visible (UV/Vis), fluorescence (FL), electrochemical detection (ECD), and mass spectrometry (MS). The integration of microcontrollers, AI-enhanced calibration routines, and IoT-enabled feedback loops has led to the rise of self-regulating analytical devices capable of real-time decision-making and autonomous operation.
View Article and Find Full Text PDFJ Dairy Sci
September 2025
TERRA Research and Teaching Centre, Gembloux Agro-Bio Tech, University of Liège, 5030 Gembloux, Belgium.
Effectively evaluating and promoting pro-grazing practices necessitates the implementation of a verification system. To address this imperative, exploration of milk composition analysis as a means to assess grazing practices has garnered substantial attention. In this study, we used component predictions from milk Fourier-transform mid-infrared (FT-MIR) spectra to construct an indicator to estimate the proportion of herbage consumed by dairy cows and another indicator to validate grazing.
View Article and Find Full Text PDFACS Cent Sci
August 2025
Hefei National Research Center of Physical Sciences at the Microscale and Department of Chemistry, University of Science and Technology of China, Hefei 230026, China.
Asymmetric organo-metal combined catalysis, which integrates the catalytic functions of chiral organocatalysts and metal complexes, enables the enantioselective formation of challenging chemical bonds and facilitates cascade transformations, often without the need for intermediate purification. Since its inception in 2001, this paradigm has evolved into a versatile strategy for the rapid construction of molecular complexity with a high level of enantioselectivity. In this Outlook, we have highlighted the most recent contributions to this field, showcasing exciting opportunities to overcome current efficiency limits.
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