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http://dx.doi.org/10.1161/RES.0000000000000718 | DOI Listing |
Front Neurosci
August 2025
Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, MD, United States.
[This corrects the article DOI: 10.3389/fnins.2023.
View Article and Find Full Text PDFBrain
July 2025
Department of Pediatrics, Kyoto University Graduate School of Medicine, Kyoto 606-8507, Japan.
X-linked myotubular myopathy is a severe congenital muscle disorder caused by pathogenic variants in the MTM1 gene, which encodes the phosphoinositide phosphatase myotubularin. Muscle biopsies from patients with X-linked myotubular myopathy exhibit distinctive histopathological features, including small, rounded myofibres with centrally located nuclei, indicating a developmental defect in muscle maturation. While earlier studies have indicated that myotubularin dysfunction causes dysregulation of mechanistic target of rapamycin complex 1 (mTORC1) signalling, the underlying mechanisms and phenotypic impact on human muscle cells remain poorly understood.
View Article and Find Full Text PDFBreast Cancer Res
June 2025
The Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, SW7 3RP, UK.
Br J Pharmacol
June 2025
Department of Biochemistry and Pharmacology, School of Biomedical Sciences, Faculty of Medicine, Dentistry and Health Sciences, The University of Melbourne, Parkville, Victoria, Australia.
Currently, the most actively investigated rapidly acting antidepressants, anxiolytics and/or anti PTSD agents, include psychedelics e.g. psilocybin, LSD, N,N-dimethyltryptamine, ayahuasca; non-hallucinogenic entactogens, e.
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