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Objective: To evaluate I-Stop-Mini surgery outcomes in urodynamic stress incontinence (USI) patients and its sonographic features at 1 year.
Methods: One hundred one patients with confirmed USI who underwent I-Stop-Mini surgery from March 2019 to February 2023 were recruited. Inclusion criteria include confirmed USI. Pelvic organ prolapse ≥ stage 2, detrusor overactivity, neurogenic bladder, high residual urine, or concomitant prolapse surgery were excluded. Primary outcomes were objective and subjective continence cure. Secondary outcomes were sonography findings of sling mobility (T), bladder neck (BN), sling to urethra percentile, and the presence of dynamic urethral kinking.
Results: Objective cure and subjective cure were 85/92 (92.4%) and 83/92 (90.2%). Significant improvement in UDS diagnosis of USI was seen pre- versus postoperatively 92/92 (100%) versus 7/92 (7.85%) p < 0.001 and change in pad weight from 22.4 ± 29.1 to 1.5 ± 3.8 g, p < 0.001. As for secondary outcome, no change in resting tape position (xt, yt), at 6months and 1 year; (18.2 ± 2.8, 17.3 ± 2.6 mm) versus (18.8 ± 2.2, 17.8 ± 2.8 mm), (p = 0.208, p = 0.237) respectively. During Valsalva (22.4 ± 3.3, 7.0 ± 2.9 mm) versus (22.8 ± 3.7, 7.5 ± 2.4 mm) (p = 0.251, p = 0.135) at 6 months and 1 year. Tape mobility unchanged, 11.3 ± 2.5 versus 11.4 ± 3.0 mm, p = 0.693. Dynamic kinking was maintained at 60% versus 59%, p = 0.877. No major complication was observed.
Conclusion: I-Stop-Mini SIS has high objective and subjective cure. Dynamic kinking, BN position (at rest and Valsalva) and mobility between 6 months and 1 year were maintained, thus promoting its continence effect.
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http://dx.doi.org/10.1111/luts.70016 | DOI Listing |
J Egypt Natl Canc Inst
September 2025
National Cancer Institute of Cairo University, Giza, Egypt.
Objectives: To balance the extended functional urinary voiding and morbidity outcomes amid Ileal W and Y-shaped contrasted to spherical ileocoecal (IC) orthotopic bladders subsequent prostate-sparing radical cystectomy (PRC) versus standard radical cystoprostatectomy (RC).
Material And Methods: Two hundred eight male bladder cancer patients were grouped into 98 RC followed by 43-W, 31-Y, and 23-IC in comparison to 110 PRC followed by 35-W, 37-Y, and 38-IC. The functional voiding outcomes were determined by detailed patients' interview and urodynamic studies (UDS).
J Inflamm Res
August 2025
Department of Urology, The Second Affiliated Hospital of Nanjing Medical University, Nanjing, 210000, People's Republic of China.
Background: Interstitial cystitis/bladder pain syndrome (IC/BPS) has become a pressing clinical issue due to its unclear etiology and severe, persistent pelvic pain. Despite extensive research, the pathogenesis of IC/BPS remains unresolved, and current treatments primarily target symptom relief rather than addressing underlying disease mechanisms. This study aimed to investigate the effects of nuclear factor erythroid 2-related factor 2 (NRF2) on IC/BPS and the potential molecular mechanisms.
View Article and Find Full Text PDFInt Urol Nephrol
September 2025
Department of Urology, Ospedale Sant'Andrea, Sapienza, University of Rome, Rome, Italy.
Purpose: The study aimed to evaluate treatment satisfaction and decisional regret in patients who underwent Adjustable Trans-Obturator Male System (ATOMS®) implantation for stress urinary incontinence (SUI).
Methods: This retrospective, observational, single-arm cohort study reviewed records of 134 patients who underwent ATOMS implantation between January 2014 and December 2021. Data collected included demographics, pre- and post-operative continence status, complications classified by Clavien-Dindo, and patient-reported outcomes using the International Consultation on Incontinence Questionnaire-Urinary Incontinence (ICIQ-UI SF).
Biomedicines
August 2025
Department of Obstetrics and Gynecology, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung 80708, Taiwan.
: De novo stress urinary incontinence (SUI) can develop postoperatively in patients without prior symptoms, and can persist beyond 6 months, posing clinical challenges. This study aimed to identify predictors of persistent de novo SUI after transvaginal mesh (TVM) surgery and to evaluate management strategies. : A retrospective review of 817 women with anterior and apical pelvic organ prolapse (POP) (stage II-IV) who underwent TVM surgery from 2013 to 2021 was conducted.
View Article and Find Full Text PDFCureus
July 2025
Urology, Sher-i-Kashmir Institute of Medical Sciences, Srinagar, IND.
Objectives To study the feasibility of bladder neck incision (BNI) in female patients with primary bladder neck obstruction in whom conservative measures have failed to show promising results. Materials and methods We included 48 female patients who had all the following features at presentation: maximum flow rate of urine <12 mL/second, inadequate funneling of the bladder neck on voiding cysto-urethrogram, post-void residual urine (PVRU) >100 mL, sustained detrusor contraction of >25 cmH2O at maximum urinary flow rate (Qmax), and a normal urethral caliber. Uroflowmetry, voiding cystometrogram, and cystourethroscopy were performed preoperatively in all patients.
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