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Background: It is unclear to what extent silent atrial fibrillation (AF) is present in subjects previously undiagnosed with AF. The recently popular 7-day patch electrocardiography (ECG) monitoring may help answer this question.
Methods: In the Kitsuki and Usuki cities in Oita Prefecture, Japan, a study was conducted among subjects who underwent 7-day patch ECG monitoring (Heartnote) for silent AF screening during the national insurance health checkup between June and November 2023. Subjects were (1) 65-74 years old and have ≥ 1 of the following risk factors: hypertension, diabetes mellitus, stroke, transient ischemic attack, and underlying heart disease (heart failure and/or previous myocardial infarction) and (2) 75 years and older.
Results: A total of 571 subjects (307 females and 264 males, mean age 75.3 ± 5.4 years) were analyzed. Silent AF was detected in 16 out of 571 subjects (2.8%). Among those aged 75 years or older, silent AF was detected in 15 out of 291 subjects (5.2%). In multivariate analysis, among age, body mass index (BMI), hypertension, diabetes, stroke, and underlying heart disease, only age was the independent predictor of silent AF detection (odds ratio: 1.16, 95% confidence interval: 1.06-1.28, p < 0.01).
Conclusions: Seven-day patch ECG monitoring during the national insurance health checkup efficiently detected silent AF in individuals aged 75 years and older.
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http://dx.doi.org/10.1111/anec.70092 | DOI Listing |
Eur J Neurol
September 2025
Digital and Predictive Medicine, Pharmacology and Clinical Metabolic Toxicology-Headache Center and Drug Abuse-Laboratory of Clinical Pharmacology and Pharmacogenomics, AOU Policlinico di Modena, Modena, Italy.
Background: Migraine is associated with an increased cardiovascular risk, including hypertension. Anti-calcitonin gene related peptide (CGRP) monoclonal antibodies (mAbs) are effective preventive treatments, but concerns have been raised about their potential hypertensive effects. Herein, we assess the early changes in blood pressure (BP) during anti-CGRP mAbs treatment in patients with migraine using 24-h Holter monitoring.
View Article and Find Full Text PDFCardiol Res Pract
August 2025
Cardiovascular Research Center, Rajaie Cardiovascular Institute, Tehran, Iran.
Long QT syndrome (LQTS) is an inherited cardiac channelopathy marked by QT interval prolongation and increased risk of life-threatening arrhythmias. While variants in , , and explain most cases, many remain genetically unexplained. This study emphasizes the value of genetic testing in diagnosis and individualized therapy.
View Article and Find Full Text PDFEur J Prev Cardiol
September 2025
Cardiology Clinic, University Center Serbia, Medical School, University Clinical Center Serbia, University of Belgrade, Belgrade, Serbia.
Aims: Chronotropic incompetence (CI) is a biomarker of cardiac autonomic dysfunction. The aim of the study is to assess the risk stratification value of CI during exercise or pharmacological stress echocardiography in patients with chronic coronary syndromes.
Methods And Results: In a prospective, multicenter, international, observational study, we enrolled 13 445 patients with known or suspected chronic coronary syndromes who underwent stress echocardiography in 19 clinical sites from 10 countries using either exercise (n = 2594), dobutamine (n = 2440), or dipyridamole (n = 8411).
J Med Econ
September 2025
iRhythm Technologies, San Francisco, CA.
Aims: Cardiac arrhythmias are common in chronic obstructive pulmonary disease (COPD) and are associated with poor outcomes. Their impact on healthcare resource utilization (HCRU) and costs is increasingly recognized. The incremental economic burden of arrhythmias in patients with COPD and the impact of early detection using ambulatory electrocardiogram (AECG) monitors remain unknown.
View Article and Find Full Text PDFJ Electrocardiol
August 2025
Cardiology, Government TD Medical College Alappuzha, Kerala, India.
We report an elderly woman who presented with cardiac arrest due to complete heart block. She developed progressive T-wave inversions in leads V3-V6 due to pacinginduced cardiac memory, accompanied by marked QTc prolongation. These repolarization abnormalities occurred despite normal electrolytes and non-obstructive coronary angiography and culminated in polymorphic ventricular tachycardia.
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