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Objectives: Multiple treatment modalities exist for treating distal femur fractures. Lateral locked plating has become the method of choice because it prevents loss of reduction due to varus collapse, but has been associated with nonunion rates of up to 30%. Titanium implants may provide a more optimal biomechanical environment for fracture healing. The primary aim of this study is to evaluate nonunion rates and risk factors for nonunion in a series of distal femur fractures stabilized with modern locked titanium implants using all nonlocking diaphyseal fixation. A secondary aim is to evaluate whether diaphyseal fixation with nonlocking screws is associated with fixation complications.
Methods: A 6-year retrospective study identified patients undergoing operative fixation of distal femur fractures with lateral locked plating and nonlocking diaphyseal fixation. Patient demographics, fracture and fixation characteristics were recorded. Follow-up data recorded included fracture union, implant failure in the setting of nonunion and secondary procedures. Statistical analyses used include test, Mann-Whitney , and logistic regression.
Results: Eighty-one fractures met inclusion criteria with 16 fractures resulting in nonunion (19.75%). Comparing union and nonunion cohorts, nonunions were found to be associated with higher body mass index ( = 0.001). Fixation construct data found nonunions had a higher average number of diaphyseal screws (4.25 vs. 3.74, = 0.038). Subgroup analysis found a nonunion rate of 4.2% (1 out of 24) in fractures with 3 diaphyseal screw fixation versus 26.3% (15 out of 57) with 4 or more diaphyseal screws ( = 0.038). No diaphyseal fixation failures were noted with nonlocking diaphyseal screw fixation.
Conclusion: Our study found using a titanium construct produced a nonunion rate of 19.75%, comparable with historic rates. Interestingly, diaphyseal fixation with more than 3 screws led to higher nonunion rates. No catastrophic failures were observed involving the diaphyseal nonlocking screw fixation.
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http://dx.doi.org/10.1097/OI9.0000000000000399 | DOI Listing |
Cureus
August 2025
Diagnostic Radiology, Mardan Medical Complex, Mardan, PAK.
Introduction: Fractures are a common occurrence in childhood, with approximately one-third of boys and girls sustaining at least one fracture before the age of 17. Both-bone forearm fractures, particularly those involving the radius and ulna, are more common in the non-dominant hand and in boys and usually involve the distal portions of both bones. If not properly treated, these injuries can have a significant impact on limb function.
View Article and Find Full Text PDFRes Vet Sci
September 2025
Department of Veterinary Medicine, Federal University of Jatai (UFJ), Jataí, State of Goiás, Brazil.
The aim of this study was to compare the compressive forces generated by Dynamic Compression Angle-Stable Interlocking Nail (DCASIN) with those of traditional Dynamic Compression Plates (DCP) and Locking Compression Plates (LCP) using synthetic diaphyseal bone models (SDBM). Three groups were established based on the fixation method (G-DCASIN, G-DCP, and G-LCP), with implants fixed to SDBM simulating a transverse fracture, comprising 10 repetitions per group. A strain-gauge load cell was positioned in the SDBM gap to measure compressive forces in kilograms, recorded 30 s after the completion of each group-specific compression technique.
View Article and Find Full Text PDFUnfallchirurgie (Heidelb)
September 2025
Klinik für Orthopädie und Unfallchirurgie, Klinikum Nürnberg, Paracelsus Medizinische Privatuniversität, Breslauer Straße 201, 90471, Nürnberg, Deutschland.
Forearm shaft fractures are the most common fractures of the upper extremity in young adults. By definition, these fractures are diaphyseal fractures; however, due to the complex functional unity formed by the forearm shaft during motion both bone forearm fractures are treated as intra-articular fractures [1, 3]. This is why the gold standard of treatment in adults is osteosynthesis.
View Article and Find Full Text PDFAdv Healthc Mater
September 2025
Smart Materials, NanoSYD, Mads Clausen Institute, University of Southern Denmark, Alsion 2, Sønderborg, DK-6400, Denmark.
This study presents a comprehensive framework combining Selective Laser Melting (SLM) of Titanium (Ti64) alloys, finite element simulation, and artificial intelligence (AI) to advance orthopedic implants' design and predictive evaluation. Dense Ti64 specimens are fabricated using ten distinct SLM parameter sets to explore the effects of volumetric energy density (VED) on mechanical behavior, porosity distribution, and microstructural integrity. Optimal VED ranges are identified to balance defect minimization and mechanical performance, with porosity levels strongly influencing tensile strength and Young's modulus.
View Article and Find Full Text PDFJ Bone Joint Surg Am
September 2025
Harvard Global Orthopaedics Collaborative, Boston, Massachusetts.
Background: Low- and middle-income countries (LMICs) are disproportionately affected by trauma, resulting in >5 million deaths annually. An essential treatment for musculoskeletal trauma is external fixation. However, in LMICs, current external fixator assemblies are unaffordable, costing patients upward of $5,000 (USD), leaving LMICs to rely on donations that fail to meet the needs of the patient population.
View Article and Find Full Text PDF