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Cross-site comparisons indicate that East Asian children typically excel on tests of executive function (EF), but interpreting this contrast is made difficult by both the heavy reliance on testing in school settings and by the scarcity of studies that assess across-site measurement invariance. Addressing these gaps, our study included remote home-based assessments of EF for 1002 children (M = 5.19 years, SD = 0.51; 49% male) from England, Hong Kong, and mainland China, as well as parental ratings of externalizing and internalizing adjustment problems (data collected between June 2021 and December 2022). The models established partial scalar invariance but did not show clear site differences. Supporting the universal importance of EF for behavioral self-regulation, EF task performance and parent-rated externalizing problems showed similar inverse associations across sites.
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http://dx.doi.org/10.1111/cdev.14264 | DOI Listing |
J Alzheimers Dis
September 2025
Paula Costa-Urrutia Medical Affairs, Terumo BCT, Edificio Think MVD, Montevideo, Uruguay.
BackgroundTherapeutic plasma exchange (TPE) with albumin replacement has emerged as a potential treatment for Alzheimer's disease (AD). The AMBAR trial showed that TPE could slow cognitive and functional decline, along with changes in core and inflammatory biomarkers in cerebrospinal fluid.ObjectiveTo evaluate the safety and effectiveness of TPE in a real-world setting in Argentina.
View Article and Find Full Text PDFNeurotrauma Rep
August 2025
Department of Radiology, Weill Cornell Medicine; New York, New York, USA.
Traumatic brain injury (TBI) impairs attention and executive function, often through disrupted coordination between cognitive and autonomic systems. While electroencephalography (EEG) and pupillometry are widely used to assess neural and autonomic responses independently, little is known about how these systems interact in TBI. Understanding their coordination is essential to identify compensatory mechanisms that may support attention under conditions of neural inefficiency.
View Article and Find Full Text PDFFront Hum Neurosci
August 2025
Baptist Medical Center, Department of Behavioral Health, Jacksonville, FL, United States.
Introduction: This study investigates four subdomains of executive functioning-initiation, cognitive inhibition, mental shifting, and working memory-using task-based functional magnetic resonance imaging (fMRI) data and graph analysis.
Methods: We used healthy adults' functional magnetic resonance imaging (fMRI) data to construct brain connectomes and network graphs for each task and analyzed global and node-level graph metrics.
Results: The bilateral precuneus and right medial prefrontal cortex emerged as pivotal hubs and influencers, emphasizing their crucial regulatory role in all four subdomains of executive function.
Appl Neuropsychol Adult
September 2025
Private rehabilitation practice, Patras, Greece.
Objective: Cognitive impairment is common in patients with schizophrenia and has been found to predict functioning and quality of life. Here we investigated the efficacy of a computer assisted cognitive rehabilitation intervention in patients with Schizophrenia.
Method: Twenty patients with schizophrenia were recruited.
Am J Psychiatry
September 2025
Department of Psychiatry, School of Medicine, Yale University, New Haven.
This review examines ketamine's neurotoxic potential across preclinical and clinical studies. The authors synthesized data from preclinical models, then integrated findings from human clinical trials of esketamine and observational studies in recreational users. Animal studies have found that repeated or high-dose subanesthetic ketamine administration results in consistent excitotoxic neuronal damage and lasting cognitive deficits, especially in perinatal animals.
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