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http://dx.doi.org/10.1016/j.scitotenv.2025.179711 | DOI Listing |
Cardiovasc Intervent Radiol
September 2025
Neuroradiologische Klinik, Kopf- Und Neurozentrum, Klinikum Stuttgart, Kriegsbergstraße 60, 70174, Stuttgart, Germany.
J Immunother Cancer
September 2025
Pharmaceutical Sciences, Washington State University, Spokane, Washington, USA
Prostate cancer (PC) is notoriously known for exhibiting an immunologically cold phenotype in the tumor immune microenvironment (TIME), leading to the need for interventions to enhance immunotherapy efficacy. Recent findings by Zhao in the identified stromal monoamine oxidase A (MAOA), a key enzyme that degrades monoamine neurotransmitters and plays a role in the neuroendocrine system, as a critical regulator of the immune response to PC. Altering MAOA levels in myofibroblastic cancer-associated fibroblasts, either genetically or pharmacologically, can reprogram PC's TIME to modulate CD8 T cell-mediated cytotoxicity through the WNT5A-Ca²-NFATC1 signaling axis, highlighting the stromal influences on CD8 T cell cytotoxic activity within the TIME.
View Article and Find Full Text PDFPLOS Glob Public Health
September 2025
Department of Pediatrics, University of Colorado, Aurora, Colorado, United States of America.
Children affected by armed conflict suffer devastating physical, emotional, and social harm. War uproots families, forcing many to flee as refugees or internally displaced persons, while others remain trapped in dangerous environments. In these crises, children face disproportionate risks-violence, exploitation, disrupted education, and collapsed healthcare systems.
View Article and Find Full Text PDFJ Robot Surg
September 2025
ORSI Academy, Melle, Belgium.
This Letter to the Editor responds to the recent publication by Patel et al. (J Robot Surg. Jul 11;19(1):370, 2025), which outlines a framework and recommendations for telesurgery.
View Article and Find Full Text PDFJ Healthc Sci Humanit
January 2024
This commentary examines the formation and impact of the Macon County Community Partners Taskforce, which was established to combat the COVID-19 pandemic in Alabama's Black Belt region. Faced with limited healthcare infrastructure, the Taskforce, a collaboration between local organizations, community leaders, and Tuskegee University, addressed the severe vulnerabilities exposed by the pandemic. The Taskforce focused on public health policy, resource management, and communication, and successfully mobilized testing, PPE distribution, and community support.
View Article and Find Full Text PDF