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Objectives: In this study, we aimed to compare the outcome after the Fontan procedure in patients after an initial ductus stenting or a surgical aortopulmonary shunt.
Methods: We reviewed infants with single ventricle and ductal-dependent pulmonary blood flow who underwent ductus stenting or an aortopulmonary shunt between 2009 and 2022, and subsequently underwent the staged Fontan procedure.
Results: A total of 93 patients were included (39 ductus stenting and 54 aortopulmonary shunts). Before the Fontan procedure, pulmonary artery pressure (9 vs 9 mmHg, P = 0.376) and pulmonary artery index (184 vs 183 mm2/m2, P = 0.988) were similar between the groups. However, the incidence of venovenous collaterals was higher in patients after ductus stenting than those after aortopulmonary shunt (35.9 vs 16.7%, P = 0.034). Median age (1.9 vs 1.8 years, P = 0.493) and weight at the Fontan procedure (12 vs 11 kg, P = 0.596) were similar between the groups. There was no in-hospital mortality in each group. The length of the intensive care unit stay (median 5 vs 5 days, P = 0.542) and hospital stay (median 17 vs 14 days, P = 0.767) were similar between the groups. During the median follow-up of 2.5 years, one late death was observed in the ductal stenting group. Freedom from reintervention (66.6 vs 82.0%, P = 0.095) and from adverse events (78.6 vs 92.2%, P = 0.488) at 5 years were similar between the groups.
Conclusions: This pilot study demonstrated comparable outcomes following the Fontan procedures between patients with single ventricle and ductal-dependent pulmonary blood flow after initial ductus stenting and those after initial aortopulmonary shunt.
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http://dx.doi.org/10.1093/icvts/ivaf118 | DOI Listing |
Int J Surg Case Rep
August 2025
Department of Oral and Maxillofacial Surgery, Dental School, Tehran University of Medical Sciences, Tehran, Iran. Electronic address:
Introduction: Congenital syngnathia, a rare craniofacial anomaly characterized by maxillomandibular fusion, has challenges in feeding, respiration, and development. While often associated with syndromes or genetic mutations, its etiology remains unclear. Here, we presented syngnathia in a preterm infant with additional anomalies, such as hemangiomas and cardiac defects.
View Article and Find Full Text PDFCardiol Young
August 2025
Department of Pediatric Cardiology, Saitama Medical University International Medical Center, Saitama, Japan.
Thoracotomy-assisted arterial duct stenting is a palliative option for patent ductus arteriosus-dependent systemic circulation, typically reserved for infants at high risk for open-heart surgery, such as those with genetic syndromes or very low birth weight. We report the first documented case of thoracotomy-assisted arterial duct stenting in a patient with Kleefstra syndrome, resulting in systemic stabilisation and long-term survival.
View Article and Find Full Text PDFPediatr Rep
August 2025
Department of Pediatrics, Chungnam National University Sejong Hospital, School of Medicine, Chungnam National University, Daejeon 35105, Republic of Korea.
There are no recorded cases of catheter-induced aortic dissection in pediatric patients. We report a unique case of a pediatric patient with Down syndrome who developed a long-standing dissecting aortic aneurysm. The patient underwent successful stent insertion 10 years after experiencing difficulty retrieving an embolized patent ductus arteriosus device.
View Article and Find Full Text PDFAnn Thorac Surg
August 2025
Ward Family Heart Center, Children's Mercy Kansas City, MO, USA; University of Missouri-Kansas City School of Medicine, Kansas City, MO, USA.
Background: The management of Pulmonary Atresia with Ventricular Septal Defect (PA/VSD) without Major Aortopulmonary Collaterals (MAPCAs) varies widely, yet multicenter outcome data is limited. This study employs a multi-institutional database to explore practice patterns, treatment strategies, and outcomes.
Methods: We identified 304 patients with PA/VSD without MAPCAs from the Pediatric Health Information System database who underwent biventricular repair between January 1, 2003, and December 31, 2023.
Curr Opin Pediatr
October 2025
Heart Institute, UPMC Children's Hospital of Pittsburgh and Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Purpose Of Review: Technological advancements and therapeutic innovations have facilitated revolutionary changes in transcatheter management of patients with congenital heart disease (CHD). In this review, we highlight the evolution of existing and newer transcatheter therapies for management of neonates with CHD.
Recent Findings: Ductus arteriosus stenting (DAS) for patients with ductal-dependent pulmonary blood flow has broadly emerged as an alternative to surgical aortopulmonary shunt placement as evidence of therapeutic equivalency, if not superiority, has been demonstrated.