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http://dx.doi.org/10.1002/epd2.70042 | DOI Listing |
Clin Genet
October 2025
Department of Neuropediatrics, CréER, ERN EpiCare, Strasbourg University Hospitals, Strasbourg, France.
We report the first known case of a 9-year-old male with early-onset epilepsy, syncope, and ictal asystole-requiring pacemaker implantation at the age of seven-associated with a pathogenic variant in FGF12.
View Article and Find Full Text PDFJ ECT
August 2025
Noninvasive Neurostimulation Therapies Laboratory, Department of Psychiatry.
Ann Neurol
August 2025
Computational Neurology, Department of Neurology and Berlin Institute of Health, Charité - Universitätsmedizin Berlin, Berlin, Germany.
Objective: Prognostication in patients with disorders of consciousness (DOCs) remains challenging because of heterogeneous etiologies, pathophysiologies and, consequently, highly variable electroencephalograms (EEGs). Here, we use EEG patterns that are well-characterizable to create a latent map that positions novel EEGs along a continuum. We asses this map as a generalizable tool to extract prognostically valuable information from long-term EEG, by predicting outcome post-cardiac arrest as a first use case.
View Article and Find Full Text PDFEpileptic Disord
August 2025
Department of Neurosurgery, Nara Medical University, Nara, Japan.
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View Article and Find Full Text PDFJ Transl Med
April 2025
Department of Pharmacology, SUNY Upstate Medical University, Syracuse, NY, USA.
Background: Long QT Syndrome Type-2 (LQT2) is due to loss-of-function KCNH2 variants. KCNH2 encodes K11.1 that forms a delayed-rectifier potassium channel in the brain and heart.
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