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Extreme temperature events related to climate change may impact blood pressure (BP). African American populations are disproportionately affected by temperature extremes due to structural inequities. We examined the association between ambient outdoor temperature and BP among participants in JHS, a cohort of African American adults residing in the tri-county area of Jackson, Mississippi. Our primary hypothesis is that daily higher outdoor ambient temperatures would be associated with lower BP. We used a linear-mixed effects model to determine the relationship between temperature and systolic and diastolic blood pressure (SBP and DBP) at three visits (N = 5296). Participants had BP readings across three visits: Visit 1 (2000-2004), Visit 2 (2005-2008), Visit 3 (2009-2013). Cardiovascular disease (CVD), diabetes, BP medication, sex, age, and visit number were included as adjustment variables. For every 1-degree Celsius higher average temperature from the mean, SBP was 0.11 mm Hg lower (95% CI: -0.14, -0.07, p < 0.001) in adjusted models. Similarly, for every 1-degree Celsius higher average temperature from the mean, DBP was 0.06 mm Hg lower (95% CI: -0.08, -0.04) in adjusted models. The associations were weakly curvilinear (inverted U-shape) with significant quadratic terms. This relationship was not modified by markers of socioeconomic status. This is the first study in the Jackson Heart Study (JHS) to investigate the association between temperature and blood pressure. Further research is needed to explore this relationship in vulnerable populations living in areas prone to extreme temperatures.
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http://dx.doi.org/10.1038/s41371-025-01026-4 | DOI Listing |
J Neurosurg Case Lessons
September 2025
Division of Pediatric Neurosurgery, Children's Hospital Los Angeles, Los Angeles, California.
Background: Intracranial hypotension (IH) is a secondary headache syndrome that can result from spontaneous or iatrogenic CSF leaks. Subdural hematomas (SDHs) are a particularly dangerous sequela of IH. Although epidural blood patch (EBP) is a recognized treatment for IH, its use in pediatric patients with SDH as a solitary intervention has not been reported.
View Article and Find Full Text PDFAnn Am Thorac Soc
September 2025
University of Gothenburg Sahlgrenska Academy, Department of Internal Medicine and Clinical Nutrition, Gothenburg, Sweden.
Introduction: Co-morbid insomnia and sleep apnea (COMISA) has been linked to poorer health outcomes and increased all-cause mortality compared with either insomnia or obstructive sleep apnea (OSA) alone.
Materials And Methods: We investigated the relationship between COMISA and uncontrolled hypertension in the Swedish CardioPulmonary BioImage Study (SCAPIS). A cross-sectional analysis including participants from the SCAPIS Gothenburg cohort (n=3832, 46% males, age 57.
Am J Respir Crit Care Med
September 2025
Aalborg University Hospital, Anaesthesia and Intensive Care, Aalborg, North Denmark Region, Denmark.
Rationale: In intensive care unit (ICU) patients lower oxygenation targets may impair long-term cognitive function, while higher targets may impair long-term pulmonary function.
Objectives: To assess the effects of a partial pressure of arterial oxygen (PaO) target of 60 vs 90 mmHg on one-year cognitive and pulmonary functions in ICU survivors of acute hypoxemic respiratory failure.
Methods: 3654 patients were randomized in the Handling Oxygenation Targets in the ICU and the Handling Oxygenation Targets in COVID-19 trials: 1916 (52.
Hypertension
September 2025
School of Population Health, University of New South Wales, Sydney, Australia (A.E.S.).
Background: Blood pressure (BP) is a common clinical measurement, now increasingly done at home. Media websites often display images of BP measurement to represent clinical medicine, but many images deviate from guidelines, potentially creating misperceptions on how measurement should be performed. We evaluated the accuracy of BP measurement images online according to the 2023 International Consensus on Standardized Clinic BP Measurement.
View Article and Find Full Text PDFPLoS Comput Biol
September 2025
Department of Mathematical and Computational Methods, National Laboratory for Scientific Computing, Petrópolis, Brazil.
Understanding cerebral circulation is crucial for early diagnosis and patient-oriented therapies for brain conditions. However, blood flow simulations at the organ scale have been limited. This work introduces a framework for modeling extensive vascular networks in the human cerebral cortex and conducting pulsatile blood flow simulations.
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