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For proper cellular growth, to prepare tissue scaffold mimicking the tissue properties is a significant challenge. Bone is a vital organ supporting the whole human body for its function. The efficiencies in its structure for a variety of reasons should properly be remedied. Bone tissue engineering (BTE) is an emerging field addressing to develop or repair bone tissue for its proper function. The bone is naturally a piezoelectric material and generates electrical stimuli because of mechanical stress. Thus, the use of piezoelectric materials to build bone tissue is of great interest in BTE. Both piezoelectric polymers and nanomaterials (NMs) are investigated for this goal. In this review, we give an overview of the recent advances in piezoelectric NMs to construct piezoelectric scaffolds in BTE.
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http://dx.doi.org/10.1080/17435889.2025.2504320 | DOI Listing |
J Craniofac Surg
September 2025
Division of Ophthalmic Plastic and Reconstructive Surgery, Sadik Eratik Eye Institute, Haydarpasa Numune Education and Research Hospital, University of Health Sciences.
Orbital floor fractures can lead to enophthalmos and diplopia, often requiring surgical intervention to restore orbital volume. Autologous iliac bone grafts are commonly used due to their biocompatibility and mechanical stability, but achieving adequate fixation remains a challenge. Traditional fixation methods, such as plates and screws, may introduce risks of foreign body reactions, graft displacement, and surgical morbidity.
View Article and Find Full Text PDFBraz Oral Res
September 2025
Universidade de Passo Fundo - UPF, School of Dentistry, Post-Graduation Program in Dentistry, Passo Fundo, RS, Brazil.
This study evaluated the influence of a customized healing abutment (CHA) placed on immediate implants. It also assessed bone ridge volume, keratinized mucosal collar, and postoperative pain. Thirty-one patients needing tooth extraction and immediate implant were selected.
View Article and Find Full Text PDFBraz Oral Res
September 2025
Universidade Federal do Rio Grande do Norte -UFRN, Department of Dentistry, Natal, RN, Brazil.
This study aimed to histomorphometrically evaluate the effect of guided bone regeneration (GBR) and two implant surfaces on the thickness and height of newly formed bone in dehiscence defects around titanium implants. Three premolars and the first bilateral molar were extracted from ten adult mongrel dogs, and 40 buccal bone dehiscences measuring 5 mm in height and 4 mm in width were created using a University of North Carolina (UNC) periodontal probe to confirm the dimensions. Forty implants were randomly assigned to one of four groups: oxidized implant surfaces (OIS, n = 10), turned/machined implant surfaces (TIS, n = 10), OIS + GBR (n = 10), and TIS + GBR (n = 10).
View Article and Find Full Text PDFPLoS Comput Biol
September 2025
Department of Genome Sciences, University of Washington, Seattle, Washington, United States of America.
Fanconi Anemia (FA) is a heritable syndrome characterized by DNA damage repair deficits, frequent malformations and a significantly elevated risk of bone marrow failure, leukemia, and mucosal head and neck squamous cell carcinomas (HNSCC). Hematopoietic stem cell gene therapy can prevent marrow failure and lower leukemia risk, but mucosal gene therapy to lower HNSCC risk remains untested. Major knowledge gaps include an incomplete understanding of how rapidly gene-corrected cellular lineages could spread through the oral epithelium, and which delivery parameters are critical for ensuring efficient gene correction.
View Article and Find Full Text PDFPLoS One
September 2025
Department of Research, Collections and Conservation, Environmental Archaeology and Materials Science, National Museum of Denmark, Kongens Lyngby, Denmark.
During the Late Bronze Age (ca. 11th-8th century BCE), far-reaching and extensive trade and exchange networks linked communities across Europe. The area around Seddin in north-western Brandenburg, Germany, has long been considered as at the core of one such networks.
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