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Women with HIV (WWH) were found to have an increased risk of abortion-related infection relative to women without HIV (WWoH) and those without HIV status documented. This relationship persisted even after accounting for factors such as mechanical injury on pelvic examination, a marker of the least safe methods of self-induction. Whether this complication in WWH is because of immunocompromise or behavioral characteristics requires additional investigation.
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http://dx.doi.org/10.1097/QAD.0000000000004176 | DOI Listing |
Am J Respir Crit Care Med
September 2025
Aalborg University Hospital, Anaesthesia and Intensive Care, Aalborg, North Denmark Region, Denmark.
Rationale: In intensive care unit (ICU) patients lower oxygenation targets may impair long-term cognitive function, while higher targets may impair long-term pulmonary function.
Objectives: To assess the effects of a partial pressure of arterial oxygen (PaO) target of 60 vs 90 mmHg on one-year cognitive and pulmonary functions in ICU survivors of acute hypoxemic respiratory failure.
Methods: 3654 patients were randomized in the Handling Oxygenation Targets in the ICU and the Handling Oxygenation Targets in COVID-19 trials: 1916 (52.
PLoS Pathog
September 2025
INSERM UMR 1291, CNRS UMR 5051, Université de Toulouse, Toulouse Institute for Infectious and Inflammatory Diseases, Toulouse, France.
Vδ1 γδ T cells are key players in innate and adaptive immunity, particularly at mucosal interfaces such as the gut. An increase in circulating Vδ1 cells has long been observed in people with HIV-1, but remains poorly understood. We performed a comprehensive characterization of Vδ1 T cells in blood and duodenal intra-epithelial lymphocytes, obtained from endoscopic mucosal biopsies of 15 people with HIV-1 on antiretroviral therapy and 15 HIV-seronegative controls, in a substudy of the ANRS EP61 GALT study (NCT02906137).
View Article and Find Full Text PDFOpen Res Eur
July 2025
Department of Community Health, Great Lakes University of Kisumu, Kisumu, Kisumu County, Kenya.
Background: Young people living with HIV in Sub-Saharan Africa account for the largest proportion of the vulnerable population in the world. Kenya has little evidence to showcase the utilization of sexual and reproductive health services among young people living with HIV. Nairobi County has one of the highest HIV burdens among adolescents and youth in the country.
View Article and Find Full Text PDFBMJ Public Health
August 2025
Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Introduction: Hepatitis C virus (HCV) infection is a substantial public health concern, particularly among individuals with opioid addiction. The methadone maintenance treatment (MMT) programmes serve as a harm reduction strategy to mitigate HIV disease spread, yet the risk of HCV infection remains high within these settings. Accurate risk prediction for HCV seroconversion is therefore crucial for improving patient outcomes.
View Article and Find Full Text PDFInterdiscip Perspect Infect Dis
August 2025
Department of Obstetrics and Gynecology, Kampala International University, Ishaka, Uganda.
Mixed vaginal infection involves the simultaneous presence of at least two types of vaginitis, including bacterial vaginosis (BV) and vulvovaginal candidiasis (VVC), BV and (TV), or TV and VVC. This condition disrupts the vaginal milieu, resulting in significant diagnostic and therapeutic challenges, recurrent infections, and increased antimicrobial resistance. This study aimed to assess the mixed vaginal infections and their predictors among women with abnormal vaginal discharges attending gynecological clinics in western Uganda.
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