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http://dx.doi.org/10.1016/j.jchf.2025.01.032 | DOI Listing |
Brain
September 2025
Center for Brain Plasticity and Recovery, Center for Aphasia Research and Rehabilitation, Departments of Neurology and Rehabilitation Medicine, Georgetown University Medical Center, Washington, DC, 20057 USA.
The role of the right hemisphere in aphasia recovery has been controversial since the 19th century. Imaging studies have sometimes found increased activation in right hemisphere regions homotopic to canonical left hemisphere language regions, but these results have been questioned due to small sample sizes, unreliable imaging tasks, and task performance confounds that affect right hemisphere activation levels even in neurologically healthy adults. Several principles of right hemisphere language recruitment in aphasia have been proposed based on these studies: that the right hemisphere is recruited primarily by individuals with severe left hemisphere damage, that transcallosal disinhibition results in recruitment of right hemisphere regions homotopic to the lesion, and that increased right hemisphere activation diminishes to baseline levels over time.
View Article and Find Full Text PDFN Am Spine Soc J
September 2025
Orthopedic Research Department, 31 Seymour St. Hartford HealthCare Bone and Joint Institute, Hartford, CT, 06106 United States.
Background: The reliance on patient reported outcomes (PROs) has substantially increased not only to augment current metrics of clinical success, but to capture the patient's perspective on the benefit of their treatment. As more PROs become utilized, the time and cost of longitudinal data collection and survey fatigue must be tempered with the benefit of the data collected. Therefore, this study sought to assess the responsiveness of the Neck Disability Index (NDI) compared to the PROMIS-10 Global Health Survey physical function T-score (PFT) and mental health T-score (MHT).
View Article and Find Full Text PDFCureus
August 2025
Internal Medicine, Aster Hospital, Dubai, ARE.
This case report describes primary meningococcal pericarditis (PMP), a rare and potentially life-threatening form of infection that may mimic idiopathic or viral pericarditis, particularly in the absence of classic signs of meningococcemia or meningitis. PMP accounts for a small proportion of meningococcal pericarditis cases. Early in its course, PMP can present without systemic features or hemodynamic instability, complicating timely recognition.
View Article and Find Full Text PDFCureus
August 2025
Internal Medicine, Hospital General Dr. Dario Fernandez Fierro, Mexico City, MEX.
Granulomatosis with polyangiitis (GPA), formerly known as Wegener's granulomatosis, is a rare form of pauci-immune vasculitis that primarily affects the respiratory tract and kidneys, though it can involve virtually any organ system. As a systemic vasculitis, it targets small- and medium-sized blood vessels and is associated with anti-neutrophil cytoplasmic antibodies (ANCA), particularly those directed against proteinase 3 (PR3). Due to its nonspecific symptoms and variable clinical presentation, GPA requires a high index of suspicion for timely diagnosis.
View Article and Find Full Text PDFFront Med (Lausanne)
August 2025
Department of Gastrointestinal Surgery, Jinhua Central Hospital, Jinhua, China.
Background: Chronic intestinal bleeding caused by vascular malformations is uncommon. Locating these small intestinal vascular malformations with precision during surgery remains a challenge. With the rapid development of digital subtraction angiography (DSA), the detection of small intestinal vascular malformations has become easier.
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