Research Progress of Autonomic Nerve Regulation in the Treatment of Myocardial Infarction.

Zhongguo Yi Xue Ke Xue Yuan Xue Bao

Department of Pharmacy,Jingmen People's Hospital, Central Hospital Affiliated to Jingchu University of Technology,Jingmen,Hubei 448000,China.

Published: April 2025


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Article Abstract

The autonomic nervous system imbalance caused by the overactivation of the sympathetic nerve and the weakened activity of the parasympathetic nerve is closely related to the occurrence and development of myocardial infarction.Autonomic nerve regulation is a new therapeutic approach aiming at inhibiting sympathetic activity and increasing parasympathetic activity.It encompasses magnetic nerve stimulation,optogenetic neuromodulation,and microinjection of botulinum toxin,which could promote the rebalance of the autonomic nervous system,thereby curbing the deterioration of the cardiac function and reducing the occurrence of ventricular arrhythmias after myocardial infarction.This paper reviews the anatomical basis,mechanisms of action,and research advances in intervention strategies of the autonomic nervous system in myocardial infarction.

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http://dx.doi.org/10.3881/j.issn.1000-503X.16150DOI Listing

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