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The autonomic nervous system imbalance caused by the overactivation of the sympathetic nerve and the weakened activity of the parasympathetic nerve is closely related to the occurrence and development of myocardial infarction.Autonomic nerve regulation is a new therapeutic approach aiming at inhibiting sympathetic activity and increasing parasympathetic activity.It encompasses magnetic nerve stimulation,optogenetic neuromodulation,and microinjection of botulinum toxin,which could promote the rebalance of the autonomic nervous system,thereby curbing the deterioration of the cardiac function and reducing the occurrence of ventricular arrhythmias after myocardial infarction.This paper reviews the anatomical basis,mechanisms of action,and research advances in intervention strategies of the autonomic nervous system in myocardial infarction.
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http://dx.doi.org/10.3881/j.issn.1000-503X.16150 | DOI Listing |
J Physiol
September 2025
Department of Cell and Molecular Biology, University of Hawaii, Honolulu, HI, USA.
Diagnoses of prediabetes and metabolic syndromes, such as metabolic-associated steatotic liver disease (MASLD), are increasing at an alarming rate worldwide, often simultaneously. A significant consequence of these is high risk of cardiovascular disease, highlighting the need for cardiac-specific therapeutics for intervention during the prediabetic stage. Recent studies have demonstrated that chemogenetic activation of the cardiac parasympathetic system through hypothalamic oxytocin (OXT) neurons provides cardioprotective effects in heart disease models by targeting excitatory neurotransmission to brainstem cardiac vagal neurons.
View Article and Find Full Text PDFSoc Cogn Affect Neurosci
September 2025
School of Psychology, Shenzhen University, Shenzhen, China.
This study investigates how anxiety influences moral judgment processes using event-related potential (ERP) techniques. Participants were instructed to rate their feelings towards other's moral and immoral acts while neural responses were recorded under safe and threat-of-shock (TOS) conditions. Participants reported significantly higher anxiety levels in the TOS context, accompanied by increased non-specific skin conductance responses (NSSCR), indicating heightened autonomic nervous system activity.
View Article and Find Full Text PDFTemperature (Austin)
April 2025
Department of Health Sciences, Swedish Winter Sports Research Centre, Mid Sweden University, Östersund, Sweden.
Heat exposure after exercise may enhance recovery of physical performance but can also impose additional physiological stress on athletes. This study investigated the effects of post-exercise infrared sauna (IRS) on adrenal and autonomic nervous system (ANS) responses and examined how these responses adapt over time during a 6-week training intervention. Forty female team-sport athletes were pair-matched into an IRS-group and a control group (CON).
View Article and Find Full Text PDFBJPsych Open
September 2025
Department of Psychosomatic Medicine and Psychotherapy, University Hospital Rechts der Isar Munich, Technical University of Munich (TUM), Germany.
Background: Dissociative disorders frequently co-occur with post-traumatic stress disorder (PTSD), yet many individuals lack adequate treatment. Existing interventions often prioritise reducing arousal over promoting safety and self-soothing, tending to neglect the bodily experience.
Aims: This randomised clinical within-person pilot study examined the effects of the nest position, a physiotherapeutic intervention designed to enhance safety and self-soothing, on patients with dissociative disorders and healthy controls (German Clinical Trials Register No.
J R Soc Interface
September 2025
ENES Bioacoustics Research Lab, CRNL, CNRS, Inserm, University of Saint-Etienne, Saint-Etienne, France.
Getting caregivers to respond to their pain cries is vital for the human baby. Previous studies have shown that certain features of baby cries-the nonlinear phenomena (NLP)-enable caregivers to assess the pain felt by the baby. However, the extent to which these NLP mobilize the autonomic nervous system of an adult listener remains unexplored.
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