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Background: The high prevalence and significant morbidity and mortality associated with chronic pain among veterans has made expansion of pain services within the Veterans Health Administration (VHA) a key priority. TelePain, in which services are provided via telehealth from central "hub" sites to patients at decentralized "spoke" sites, is one such model with positive implementation findings to date. However, the staff effort and cost of implementation have yet to be examined when considering TelePain or similar virtual hub-and spoke models of specialty pain care, information that is critical for expansion of services.
Methods: Using an established time-based activity tracker designed for implementation facilitation, study staff tracked minutes spent on implementation activities at 11 spoke sites. Annual salaries were extracted to calculate an average cost per minute for each personnel type. Costs per personnel minute were combined with activity data to calculate costs of implementation activities at spoke sites. Implementation reach outcomes for the first 36 months of implementation were extracted from the electronic health record. Service utilization data was combined with cost data to calculate cost per patient reached and per clinical encounter achieved at each site.
Results: Total facilitation costs (range: $1,746-$7,978) and unique patients reached (range: 2-46) varied considerably across spoke sites and greater staff implementation efforts (measured in time or cost) were not associated with greater numbers of patients reached. Therefore, costs per patient reached also varied widely (range: $120-2,569) across spoke sites. Key challenges included high rurality and small clinic size; insufficient engagement of frontline providers; lack of referral options for high acuity patients; and lack of existing programming within which to situate pain services.
Conclusions: At spoke sites where patients were consistently referred and reached, costs were relatively modest, particularly compared to the high cost of untreated chronic pain, suggesting the potential impact of this model at scale. However, in spoke sites where referrals and encounters were low during initial implementation, cost per patient was high. Findings highlight the need for better methods for tailoring of facilitation interventions to spoke site's individual needs to maximize impact.
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http://dx.doi.org/10.1186/s43058-025-00729-6 | DOI Listing |
Front Med (Lausanne)
August 2025
Care Access Research LLC, Boston, MA, United States.
Introduction: Recruitment and retention remain critical challenges in clinical trials, particularly in neurodegenerative diseases, which require large participant populations, rigorous screening, and prolonged follow-up periods. Care Access is a global research site management organization that operates clinical trial sites employing various operational models. This study evaluates the operational performance of Care Access site models-including traditional sites, hub-and-spoke, and decentralized community-integrated research (DCIR) sites-within a Phase 3 neurodegenerative disease trial, focusing on their relative efficiency in recruitment, randomization, and retention.
View Article and Find Full Text PDFPLoS One
September 2025
Division of NCD, Indian Council of Medical Research, New Delhi, India.
Introduction: Integrated emergency care systems are essential for achieving universal health coverage and managing time-sensitive conditions. In India, emergency care remains fragmented, with limited resources and coordination across healthcare tiers. The INDIA-EMS study aims to develop and evaluate a patient-centric, high-quality integrated emergency care model in diverse Indian districts.
View Article and Find Full Text PDFBMC Public Health
August 2025
Elizabeth Glaser Pediatric AIDS Foundation, Washington DC, USA.
Introduction: Despite significant advances in HIV diagnosis and access to ART, many patients still present with advanced HIV disease (AHD). We assessed the effect of an optimized AHD care package on the screening and diagnosis of opportunistic diseases among clients enrolled in AHD care.
Methods: This non-randomized cluster design was conducted using a hub-and-spoke model.
JAMA Netw Open
August 2025
Department of Pediatrics, University of Pittsburgh School of Medicine (UPMC), UPMC Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania.
Importance: Care is commonly sought for pediatric acute respiratory tract infections (ARTIs). The site where families seek ARTI care affects continuity, quality, and costs, but how parents of young children balance tradeoffs between care sites is unknown.
Objectives: To evaluate preferences for attributes of ARTI care sites among parents of young children using a discrete choice experiment (DCE).
Current models of vaccination coverage screening and surveillance might miss underserved populations whose only health care access occurs in emergency departments (EDs). During April-December 2024, a survey of non-critically ill adult patients evaluated in 10 EDs in eight U.S.
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