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http://dx.doi.org/10.1165/rcmb.2024-0441LE | DOI Listing |
J Heart Lung Transplant
September 2025
Department of Medicine, University of California, San Francisco, CA; Department of Anesthesia and the Cardiovascular Research Institute, University of California, San Francisco, CA.
J Heart Lung Transplant
September 2025
Department of Cardiothoracic and Vascular Surgery, Deutsches Herzzentrum der Charité (DHZC), Augustenburger Platz 1, 13353 Berlin, Germany; Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Charitéplatz 1, 10117 Berlin, Germany
J Thorac Cardiovasc Surg
September 2025
Department of General Thoracic and Breast and Endocrinological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan. Electronic address:
Objective: Currently, the two methods used to preserve lungs from uncontrolled donation after circulatory death-topical cooling and inflation-result in the suboptimal utilization of lungs. This study aimed to introduce an approach that combines cooling and inflation to investigate whether it improves lung conditions in a swine model, even if the lungs had been damaged with long-term warm ischemia, such as in out-of-hospital cardiac arrest.
Methods: Donor lungs subjected to 1.
J Thorac Cardiovasc Surg
September 2025
Latner Thoracic Research Laboratories, Toronto General Hospital Research Institute, University Health Network, Toronto, ON, Canada; Toronto Lung Transplant Program, Ajmera Transplant Centre, University Health Network, Toronto, ON, Canada; Division of Thoracic Surgery, Department of Surgery, Universi
Objectives: To report the impact of ex vivo lung perfusion (EVLP) on lung transplantation practices and clinical outcomes. This study presents the largest single-centre EVLP experience to date, highlighting how EVLP has transformed clinical lung transplantation with expansion of donor access, program growth, and the safe use of extended criteria donor lungs.
Methods: We conducted a retrospective analysis of 1,000 consecutive EVLP procedures performed between 2008 and 2024 at University Health Network's Toronto General Hospital.
Cureus
August 2025
Department of Anatomy, A.T. Still University, Kirksville, USA.
Introduction: Normal anatomical variations between the right and left lungs can affect function and disease presentation; a better understanding of these variations is necessary for optimizing thoracic procedures. Therefore, the current study investigated the lung pathologies of donor bodies to enhance understanding of anatomical variations when performing surgical lung resections, lobectomies, and other thoracic procedures.
Methods: The lungs of 31 donor bodies from A.