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Objective: To determine optimal CT perfusion (CTP) imaging parameters for evaluating the canine prostate and to assess the diagnostic utility of CTP combined with cytopathologic evaluation and B-Raf proto-oncogene (BRAF) gene mutation testing in dogs with prostate adenocarcinoma.
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Intracellular lymphocyte protein biomarkers for early radiological triage in the human population.
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In the event of a large-scale radiological or nuclear emergency, a rapid, high-throughput screening tool will be essential for efficient triage of potentially exposed individuals, optimizing scarce medical resources and ensuring timely care. The objective of this work was to characterize the effects of age and sex on two intracellular lymphocyte protein biomarkers, BAX and p53, for early radiation exposure classification in the human population, using an imaging flow cytometry-based platform for rapid biomarker quantification in whole blood samples. Peripheral blood samples from male and female donors, across three adult age groups (young adult, middle-aged, senior) and a juvenile cohort, were X-irradiated (0-5 Gy), and biomarker expression was quantified at two- and three-days post-exposure.
View Article and Find Full Text PDFHair analysis for monitoring adherence to inhaled respiratory medications: possibilities and limitations.
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Department of Clinical Pharmacy and Pharmacology, University of Groningen, and University Medical Center Groningen, Groningen, The Netherlands.
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Automated volumetric MRI quantification of body fat and skeletal muscle in the UK Biobank: technical validation against expert manual segmentations and comparison with single-slice techniques.
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