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Unlabelled: Malnutrition and overweight are significant public health challenges, especially in low- and middle-income countries. In the Amazon, high rates of malnutrition and the alarming rise of obesity highlight persistent regional inequalities. Therefore, the aim of this study was to analyze spatial distributions and temporal trends of malnutrition among children under five, adults, and elderly individuals in primary healthcare services across municipalities in the Legal Amazon from 2013 to 2023.
Methods: This ecological study used data from the Food and Nutritional Surveillance System (SISVAN). The analysis included the prevalences of underweight, overweight, and obesity, stratified by year, sex, and federative unit. Spatial distributions were analyzed using QGIS version 3.22, and temporal trends were assessed with Joinpoint version 4.6 and expressed as annual percentage changes (APCs) and 95% confidence intervals (95% CIs).
Results: Between 2013 and 2023, SISVAN monitored 10,451,758 children under five years, 30,831,720 adults, and 4,456,650 elderly individuals in the Legal Amazon. Stunting in children under five years decreased from 20.45% to 15.30%, with a significant downward trend (APC: -2.7; 95% CI: -3.7; -1.6). Childhood overweight exhibited a general downward trend but with notable fluctuations. Overweight in adults increased from 48.85% to 64.64%, and obesity from 17.10% to 28.49%, both showing significant upward trends. For the elderly, underweight decreased from 17.47% to 13.04%, with a downward trend until 2018, while overweight increased from 42.35% to 48.22%, with a significant upward trend until 2017.
Conclusions: Despite progress in reducing childhood underweight, its prevalence in the Legal Amazon remains high compared to national averages. Significant regional disparities and rising overweight rates among adults and elderly individuals indicate a need for targeted public health strategies to address these nutritional issues.
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http://dx.doi.org/10.3390/nu17061054 | DOI Listing |
Nat Commun
September 2025
Institute of Physics, University of São Paulo, São Paulo, Brazil.
The Amazon rainforest is one of Earth's most diverse ecosystems, playing a key role in maintaining regional and global climate stability. However, recent changes in land use, vegetation, and the climate have disrupted biosphere-atmosphere interactions, leading to significant alterations in the water, energy, and carbon cycles. These disturbances have far-reaching consequences for the entire Earth system.
View Article and Find Full Text PDFBMC Infect Dis
August 2025
Instituto de Medicina Tropical Alexander von Humboldt, Universidad Peruana Cayetano Heredia, Lima, 15102, Peru.
Background: Chromoblastomycosis (CBM) is a chronic subcutaneous mycosis caused by dematiaceous fungi that mainly affects rural workers in tropical and subtropical regions. The disease poses a treatment challenge due to its refractory nature and high relapse rate. To date, few cases have been reported in Peru.
View Article and Find Full Text PDFmedRxiv
July 2025
Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02115, USA.
The rapid expansion of molecularly informed therapies in oncology, coupled with evolving regulatory FDA approvals, poses a challenge for oncologists seeking to integrate precision cancer medicine into patient care. Large Language Models (LLMs) have demonstrated potential for clinical applications, but their reliance on general knowledge limits their ability to provide up-to-date and niche treatment recommendations. To address this challenge, we developed a RAG-LLM workflow augmented with Molecular Oncology Almanac (MOAlmanac), a curated precision oncology knowledge resource, and evaluated this approach relative to alternative frameworks (i.
View Article and Find Full Text PDFRev Panam Salud Publica
August 2025
Oswaldo Cruz Foundation, Brasília, Brazil Oswaldo Cruz Foundation Brasília Brazil.
Objective: To systematically identify and critically assess indicators used globally and in Brazil to monitor health outcomes related to Sustainable Development Goal (SDG) 3, with an emphasis on identifying those most suitable for the Legal Amazon region.
Methods: This rapid review examined global initiatives to achieve SDG 3 and their applicability to the Legal Amazon. Systematic reviews and overviews were included, with no language restrictions, considering studies published from 2015 onwards.
Sci Total Environ
August 2025
Univ. Grenoble Alpes, Univ. Savoie Mont Blanc, CNRS, IRD, IFSTTAR, ISTerre, 38000 Grenoble, France.
Artisanal and small-scale gold mining is responsible for deforestation and habitat degradation in Amazonian ecosystems due to soil reworking and increased turbidity in surrounding rivers. In French Guiana, legal mines are required to perform rehabilitation after gold extraction. To assess the successfulness of this rehabilitation, the temporal evolution of particles and metal(loid)s (mercury, lead, arsenic) export was measured, as well as several parameters linked to soil functions (soil carbon and nitrogen, microbial diversity, enzymatic activities).
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