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Context: Cervical disc arthroplasty (CDA) is a safe and effective treatment for cervical spine conditions, with increasing utilization. As the population over 65 grows, understanding the suitability of CDA in older patients is critical.
Aims: This study evaluates differences in postoperative complications, hospital course, and costs between patients aged 18 and 65 and those over 65 undergoing CDA.
Settings And Design: This was a retrospective cohort study using the National Inpatient Sample, a nationally representative database of U.S. hospital discharges.
Subjects And Methods: Patients undergoing single-level CDA from 2016 to 2020 were identified. The cohort was divided into two groups: 18-65 years and >65 years. Propensity score matching (1:5) was applied based on sex, race, obesity, chronic lung disease, and the Elixhauser Comorbidity Index. Outcomes included postoperative complications, length of stay (LOS), hospital costs, and discharge disposition. Statistical significance was set at P < 0.05.
Statistical Analysis Used: Propensity score matching ensured group balance. Chi-square tests and Student's t-tests assessed outcomes, with a Benjamini-Hochberg adjustment for multiple comparisons.
Results: After matching, 4550 cases from the 18 to 65 years of group and 910 from the >65 group were analyzed. Dysphagia rates were higher in the older cohort (8.8% vs. 3.8%, P = 0.007). LOS was significantly longer for older patients (2.15 ± 0.20 days vs. 1.38 ± 0.04 days, P < 0.001). Hospital costs were higher in the >65 group ($25,900 ± 1000 vs. $22,500 ± 400, P = 0.005), and nonroutine discharge was more common (19.2% vs. 7.1%, P < 0.001).
Conclusions: Older patients undergoing CDA experience more complications, longer hospital stays, and higher costs, highlighting the need for tailored care strategies.
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http://dx.doi.org/10.4103/jcvjs.jcvjs_21_25 | DOI Listing |
Pediatr Blood Cancer
September 2025
Centre for Reviews and Dissemination, University of York, York, UK.
Acute leukaemias are the commonest cancers in children and young people (CYP). Off-treatment surveillance is assumed to improve relapse detection, but whether this affects subsequent survival and quality of life is unclear. This systematic review searched 13 databases and two trial registries in December 2022.
View Article and Find Full Text PDFJ Dent Educ
September 2025
Department of Oral and Maxillofacial Surgery, Stomatological Hospital, School of Stomatology, Southern Medical University, Guangzhou, P. R. China.
Background: Virtual reality (VR) and artificial intelligence (AI) technologies have advanced significantly over the past few decades, expanding into various fields, including dental education.
Purpose: To comprehensively review the application of VR and AI technologies in dentistry training, focusing on their impact on cognitive load management and skill enhancement. This study systematically summarizes the existing literature by means of a scoping review to explore the effects of the application of these technologies and to explore future directions.
Anal Chim Acta
November 2025
Department of Breast Surgery, General Surgery Center, First Hospital of Jilin University, Changchun, PR China. Electronic address:
Background: Breast-conserving surgery (BCS) is the primary surgical approach for patients with breast cancer. The accurate determination of surgical margins during BCS is critical for patient prognosis; however, time constraints and limitations in current pathological techniques often prevent pathologists from performing this assessment intraoperatively. The inability to reliably assess margins during surgery can lead to incomplete tumor removal and the need for additional surgeries.
View Article and Find Full Text PDFWorld Neurosurg
September 2025
Department of Neurosurgery, St. Marianna University School of Medicine, Kawasaki, Japan. Electronic address:
Although subdural drain (SDD) placement reduces recurrence after burr-hole surgery for chronic subdural hematoma (CSDH), complications have led our institution to discontinue its routine use. During the first year following this change, the recurrence rate was 14.6%, comparable to the recurrence rate observed prior to discontinuation.
View Article and Find Full Text PDFClinics (Sao Paulo)
September 2025
Department of Physiological Sciences, Universidade Federal do Espírito Santo, Vitória, ES, Brazil.
Background: Endometriosis diagnosis is challenging due to non-specific symptoms that overlap with other gynaecological conditions. This study proposes a non-invasive Machine Learning (ML) ‒ based urine test using Attenuated Total Reflection Fourier Transform Infrared (ATR-FTIR) spectroscopy for rapid, high-throughput screening.
Methods: A total of 302 symptomatic patients presenting with pelvic pain and MRI referral indications were recruited.