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Nonblind image deconvolution/deblurring aims at restoring sharp images from their noisy blurred versions using an associated blur kernel with potential inaccuracy. Current deep learning (DL) models of nonblind image deconvolution (NBID) predominantly reply on ground truth (GT) images for supervision, which restricts their applicability to certain real-world scenarios such as scientific imaging. This article proposes a fully unsupervised DL approach for NBID, utilizing a GT-free end-to-end training process that adeptly handles both measurement noise and kernel error. Specifically, in the absence of GT images, a self-reconstruction loss is proposed to handle measurement noise, by effectively emulating its supervised counterpart. Recognizing the likely occurrence of kernel error during both training and testing data, we introduce a self-ensemble loss function and an ensemble inference scheme, anchored by a phase-keeping kernel perturbation strategy. Furthermore, a shifting mechanism is integrated so as to the loss functions to resolve the shift ambiguity caused by kernel error. Extensive experiments show the superiority of our proposed approach over existing unsupervised NBID methods, as well as its competitive performance against some of the recent supervised methods.
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http://dx.doi.org/10.1109/TNNLS.2025.3556867 | DOI Listing |
Int J Cardiol Heart Vasc
October 2025
Department of Cardiothoracic Surgery, Friedrich-Schiller-University Jena, University Hospital Jena, Germany.
Background: Cardiac biomarkers are important components for diagnosing perioperative myocardial infarction (MI). Efforts to detect MI by biomarker-release only faced heavy criticism, because cardiac biomarker-release has also been observed in situations that are not always related to cell death (e.g.
View Article and Find Full Text PDFPLoS One
August 2025
Neuromodulation and Pain Lab (NeuroPain), Egas Moniz Interdisciplinary Research Center (CiiEM), Almada, Portugal.
The Murph workout, one of the most challenging CrossFit® workouts, demands endurance and high intensity. This WOD (Workout of the Day) includes a 1-mile run, 100 pull-ups, 200 push-ups, 300 air squats, and another 1-mile run, typically performed while wearing a weighted vest. Due to its high physical demands, athletes commonly experience Delayed Onset Muscle Soreness (DOMS), characterized by increased sensitivity, fatigue, and reduced muscle function.
View Article and Find Full Text PDFJ Intensive Care Med
August 2025
Institute of Critical Care Medicine, Icahn School of Medicine Mount Sinai, New York, NY, USA.
BackgroundCentral line placement is a very common inpatient procedure and the internal jugular (IJ) vein is the most commonly accessed site. Complications associated with this procedure include pneumothorax, hemothorax and pain which may be caused by accidental visceral injury with needle over-penetration.Research QuestionExtrapolating approximate needle length required to access sonographic mid-point of the internal jugular (IJ) vein.
View Article and Find Full Text PDFEClinicalMedicine
June 2025
Nuffield Department of Women's & Reproductive Health, University of Oxford, Oxford, United Kingdom.
Background: Advances in artificial intelligence (AI) have triggered interest in using intelligent systems to improve prenatal detection of fetal congenital heart defects (CHDs). Our aim is to systematically examine the current literature on diagnostic performance of AI-enabled prenatal cardiac ultrasound.
Methods: This systematic review and meta-analysis was registered with PROSPERO (CRD42024549601).
Mol Autism
July 2025
CliniKids, The Kids Research Institute Australia, Perth, Australia.
Background: Eye-tracking could expedite autism identification/diagnosis through standardisation and objectivity. We tested whether autism assessment, with Classification Algorithm derived from gaze fixation durations, would have good accuracy (area under the curve [AUC] ≥ 0.80) to differentiate 2-4-year-old autistic from non-autistic children.
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