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Article Abstract
Background: We report a case of fungemia in a 77-year-old immunocompromised male with gastrointestinal abnormalities including achalasia, gastroparesis, and prior esophagectomy. He presented with sepsis, gastric ischemia, and pleural effusion. To date, only 2 prior cases of infection have been reported, both involving nonbloodstream infections.
Methods: We reviewed the existing literature and compared clinical, diagnostic, and treatment characteristics across all identified cases.
Results: has been identified in critically ill, immunocompromised patients with gastrointestinal anatomic abnormalities, underlying malignancy, and disease. Diagnosis relies on advanced methods such as matrix-assisted laser desorption/ionization time-of-flight mass spectrometry and DNA sequencing. Antifungal treatments (caspofungin, fluconazole, micafungin) have resulted in favorable outcomes.
Conclusions: This review highlights as a rare opportunistic pathogen and provides the first evidence for as a bloodstream pathogen in humans. Prompt identification and antifungal therapy are critical for managing infections.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC12015476 | PMC |
| http://dx.doi.org/10.1093/ofid/ofaf209 | DOI Listing |
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