Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Background: Hypertension is among the most complex global public health concerns. Hypertension and kidney diseases share a strong correlation. The existence of microalbuminuria signifies early renal impairment. Left ventricular hypertrophy (LVH) is one of the early indicators of target organ damage in hypertension individuals.
Objective: To evaluate the connection between microalbuminuria and left ventricular mass index (LV mass index), as well as systolic and diastolic blood pressure, in people with primary hypertension.
Methods: This cross-sectional analytical study was conducted for about 2 years and included 125 essential hypertensive patients who met JNC-8 criteria for ambulatory hypertension. Urine albumin excretion was estimated by the method of immunoturbidimetry. 2D echocardiography was performed to determine the LV mass index. Statistical analysis by standard methods to measure proportions and Chi-square test for analyzing association between variables was used.
Results: Out of the 125 patients, 50 (40.0%) patients had LVH and 51 (40.8%) patients had microalbuminuria. Patients with LVH exhibited a prevalence of microalbuminuria at 72%. Microalbuminuria was significantly related with diastolic blood pressure and LV mass index.
Conclusion: This study shows that microalbuminuria is very common in essential hypertension with LVH. There is a significant association of microalbuminuria with LV mass index and diastolic blood pressure in patients of primary hypertension.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC12007793 | PMC |
| http://dx.doi.org/10.4103/jfmpc.jfmpc_1173_24 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Prediabetic cardiomyopathy is attenuated by hypothalamic PVN oxytocin neuron activation.
J Physiol
September 2025
Department of Cell and Molecular Biology, University of Hawaii, Honolulu, HI, USA.
Diagnoses of prediabetes and metabolic syndromes, such as metabolic-associated steatotic liver disease (MASLD), are increasing at an alarming rate worldwide, often simultaneously. A significant consequence of these is high risk of cardiovascular disease, highlighting the need for cardiac-specific therapeutics for intervention during the prediabetic stage. Recent studies have demonstrated that chemogenetic activation of the cardiac parasympathetic system through hypothalamic oxytocin (OXT) neurons provides cardioprotective effects in heart disease models by targeting excitatory neurotransmission to brainstem cardiac vagal neurons.
View Article and Find Full Text PDFChanges in antral follicle dynamics following weight loss in women with polycystic ovary syndrome.
Hum Reprod
September 2025
Division of Nutritional Sciences, Cornell University, Ithaca, NY, USA.
Study Question: Does weight loss from a hypocaloric dietary intervention improve antral follicle dynamics in women with PCOS?
Summary Answer: During a 3-month hypocaloric dietary intervention, women with PCOS who experienced clinically meaningful weight loss showed more organized antral follicle development including fewer recruitment events, but no change in the overall frequency of selection, dominance, or ovulation.
What Is Known Already: There is a spectrum of disordered antral follicle development in women with PCOS including excessive follicle recruitment and turnover, decreased frequency of selection and dominance, and failure of ovulation. Lifestyle intervention aimed at weight loss is recommended to improve metabolic health in women with PCOS yet benefits on ovarian follicle development and ovulation are unclear.
Relationship between salt and blood pressure in indigenous and non-indigenous populations.
Cien Saude Colet
August 2025
Departamento de Ciências Fisiológicas, Centro de Ciências da Saúde, Universidade Federal do Espírito Santo. Av. Marechal Campos 1468. 29040-090 Vitória ES Brasil.
Objective: to compare the effect of salt consumption on blood pressure (BP) of an indigenous and of a non-indigenous population in Brazil.
Design: the studies were carried out in the years of 1999-2004 in an urban population of Vitória (n = 1,663), the capital of Espírito Santo State, and in an indigenous population settled in a reserve of Aracruz (n = 663). Salt consumption was evaluated by a 12-hour overnight urine collect.
Impact of Urate-Lowering Therapy after Percutaneous Coronary Intervention on the Long- Term Prognosis of Patients with Hyperuricemia.
Kardiologiia
September 2025
Department of Cardiology, The Ninth Medical Center, Chinese PLA General Hospital.
Background Hyperuricemia (HUA) frequently coexists with coronary artery disease (CAD) and is linked to adverse cardiovascular outcomes. The long-term impact of urate-lowering therapy (ULT) on clinical outcomes, including all-cause mortality and major adverse cardiovascular events (MACEs), in CAD patients after percutaneous coronary intervention (PCI) has not been determined. That was the aim of this study.
View Article and Find Full Text PDFEvaluation of Left Atrial Function in Patients with Hypertensive Heart Disease and Preserved Ejection Fraction Using Real-Time, Three- Dimensional Speckle Tracking Imaging.
Kardiologiia
September 2025
Second Affiliated Hospital of Chongqing Medical University, Department of Ultrasound Medicine.
Objective This research investigated the application of real-time, three-dimensional speckle tracking imaging (RT-3D-STI) to evaluate left atrial (LA) function in individuals suffering from hypertensive heart disease (HHD) and heart failure with preserved ejection fraction (HFpEF).Material and methods This retrospective study included 100 patients with HHD and HFpEF hospitalized from August 2023to June 2024 (HFpEF group). 100 healthy individuals undergoing physical examinations comprised the control group.
View Article and Find Full Text PDF