Spondylodiscitis in an Immunocompetent Patient With Recurrent Endocarditis; A Clinical Case Report.

Introduction: Fungal endocarditis is a very uncommon and deadly illness that causes inflammation in the heart's lining, including the valves. endocarditis is the second most common cause of prosthetic endocarditis, especially the aortic valve, after spp. endocarditis can occur on native and prosthetic valves, even in immunocompetent hosts.

Case Report: In this article, we describe a case of recurrent aortic-valve endocarditis occurring in a Caucasian man without previously known immunocompromised status with multiple brain septic emboli and spondylodiscitis. The patient was successfully responsive to liposomal amphotericin B.

Discussion: Early recognition in patients with underlying immunosuppressive conditions and immunocompetent hosts is critical to decreasing the mortality rate. Aspergillosis must be considered in every patient with a prior valve replacement history and culture-negative endocarditis. Surgical debridement and appropriate antifungal agents are required to resolve the problem.