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We compared self-reported vaccination to vaccine card data to assess concurrency in a sample of Black young adults in Georgia, Alabama, and North Carolina. We described vaccine card versus self-reported data over time and examined discrepancies in reporting between these two sources. Results indicated strong currency suggesting collection of self-reported data may be an acceptable proxy to requiring official vaccine documentation. However, since 58 % of participants did not upload a vaccine card, finding should be applied with caution. Minor differences were found and were generally due to boosters that were self-reported but were not on cards. The discrepancy in number of vaccines and boosters was likely because COVID-19 vaccination has become routine and vaccine cards are not being updated regularly. At this stage in the pandemic and for other vaccinations that become routine and are administered at pharmacies, self-report may be a reliable indication of the number of vaccinations received.
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http://dx.doi.org/10.1016/j.vaccine.2025.127136 | DOI Listing |
Drug Saf
September 2025
Medicines and Healthcare products Regulatory Agency (MHRA), Safety and Surveillance, 10 South Colonnade, Canary Wharf, London, E14 4PU, UK.
Introduction: Yellow Card Vaccine Monitor (YCVM) was established by the UK Medicines and Healthcare products Regulatory Agency (MHRA) to facilitate active monitoring of adverse drug reactions following COVID-19 vaccination and further characterise safety in populations under-represented in clinical trials.
Objective: This study explored the profile of individuals registered to the YCVM platform and the suspected adverse drug reactions reported following a COVID-19 vaccination on this data platform.
Methods: Using a stratified random selection approach, individuals were invited to register and actively contacted to seek further information on the vaccines received and adverse reactions they experienced.
Front Microbiol
August 2025
Center for Microbiology Research, Kenya Medical Research Institute, Nairobi, Kenya.
Introduction: Enterotoxigenic (ETEC) is a significant cause of diarrheal morbidity and mortality among children under 5 years, particularly in low and middle-income countries. This study aimed to determine the prevalence of ETEC and associated risk factors among children under five presenting with diarrhea in health facilities in Mukuru slums of Nairobi, Kenya, where poor sanitation and hygiene practices are prevalent.
Methods: Using a cross-sectional design, we recruited 387 children under five years of age with acute diarrhea.
Background: Sotrovimab is a neutralising monoclonal antibody targeting the SARS-CoV-2 spike protein. We aimed to evaluate the efficacy and safety of sotrovimab in the RECOVERY trial, an investigator-initiated, individually randomised, controlled, open-label, adaptive platform trial testing treatments for patients admitted to hospital with COVID-19.
Methods: Patients admitted with COVID-19 pneumonia to 107 UK hospitals were randomly assigned (1:1) to either usual care alone or usual care plus a single 1 g infusion of sotrovimab, using web-based unstratified randomisation.
Hum Vaccin Immunother
December 2025
Department of Pediatrics, University of California, Los Angeles, CA, USA.
Approximately two out of three children and one out of four adults experience significant anxiety related to vaccination, which can result in vaccine avoidance. Promoting patient autonomy by empowering individuals to choose coping strategies that work best for them can enhance the overall vaccination experience. The CARD system is an innovative, patient-centered approach that improves the vaccination experience for both patients and healthcare providers.
View Article and Find Full Text PDFAnn Ib Postgrad Med
March 2025
Department of Paediatrics, University College Hospital, Ibadan, Nigeria.
Background: The "Child health card" (CHC) is integral to monitoring a child's growth and assessing development to support the early detection of malnutrition and prompt intervention. CHC is also valuable in keeping track of a child's vaccinations. There are limited studies on knowledge and utilization of CHC in Oyo state, Nigeria.
View Article and Find Full Text PDF