98%
921
2 minutes
20
Objective: This study evaluated healthcare workers' occupational exposure to inhaled drugs during drug reconstitution and handling tasks, focusing on compliance with occupational exposure limits (OELs).
Methods: Ten nurses and pharmacy technicians were monitored during an 8-hour shift to measure inhalable particle concentrations using a portable sampling device.
Results: Inhalable particle concentrations ranged from <15 to 381 μg/m 3 (arithmetic mean 83 μg/m 3 ). Exposure to drugs in hazardous drug classes (HDCs) 1, 2, and 3 complied with OELs, while exposure to drugs in HDCs 4 and 5 exceeded OELs, highlighting the need for enhanced protective measures.
Conclusions: No additional precautions are needed for drugs in HDCs 1, 2, and 3, but dust exhaust or biosafety cabinets are recommended for handling drugs in HDCs 4 and 5.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC12237139 | PMC |
http://dx.doi.org/10.1097/JOM.0000000000003401 | DOI Listing |
Infection
September 2025
Research Unit for Environment, Work and Health, Department of Public Health, Aarhus University, Bartholins Allé 2, Building 1260, Aarhus C, DK-8000, Denmark.
Background: Livestock-MRSA (methicillin-resistant Staphylococcus aureus) can cause infections in persons without known contact to livestock, but the route of transmission is unclear. We investigated whether the risk of livestock-MRSA infection among persons with no known contact to livestock is associated with the number of pig farms near the home, and whether this association is affected by the upwind/downwind location of the farms.
Methods: Register-based case-control study of 518 persons from Denmark with clinical infections with livestock-MRSA in 2016-2021 and no known exposure to livestock, and 4,944 matched controls.
Arch Toxicol
September 2025
Section of Occupational Medicine, Department of Diagnostics and Public Health, University of Verona, Verona, Italy.
Glyphosate, a widely used herbicide, has raised concerns regarding its impact on human health and the environment due to its widespread and excessive use. Adverse effects on the immune system have been reported. In this study, 26 vineyard workers in Veneto vineyards were examined before and after glyphosate applications to investigate possible immune parameter changes.
View Article and Find Full Text PDFInt Arch Occup Environ Health
September 2025
Department of Mechanical Engineering, Politecnico di Milano, Milan, Italy.
Purpose: To investigate the role of personal risk factors in the occurrence of the vascular, neurological and fibroproliferative disorders of the hand-arm vibration syndrome (HAVS) in workers groups exposed to hand-transmitted vibration (HTV).
Methods: HAVS prevalence and incidence data were pooled across a series of cross-sectional studies (total sample: 1272 HTV workers, 579 controls) and prospective cohort studies (total sample: 377 HTV workers, 138 controls) conducted in Central and North-Eastern Italy. The pooled studies included detailed individual-level information about HTV exposure, personal risk factors, medical comorbidities and HAVS disorders.
J Forensic Sci
September 2025
School of Criminology & Criminal Justice and Griffith Criminology Institute, Griffith University, Nathan, Queensland, Australia.
Forensic staff play a crucial role in law enforcement through providing specialist services to police agencies in criminal investigations. Given the unique work, including frequent exposure to potentially distressing material, administrative workloads, and other work-related pressures, forensic staff are at risk of increased occupational stress. The current study examined the demands and resources associated with stress-related outcomes among forensic staff.
View Article and Find Full Text PDFEnviron Mol Mutagen
September 2025
Department of Biology, University of Ottawa, Ottawa, Ontario, Canada.
Long-duration spaceflight exposes astronauts to various stressors that can alter human physiology, potentially causing immediate and long-term health effects. These stressors can damage biomolecules, cells, tissues, and organs, leading to adverse outcomes. Developing adverse outcome pathways (AOPs) relevant to radiation exposure can guide research priorities and inform risk assessments of future space exploration activities.
View Article and Find Full Text PDF