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Background: Hyperammonemic encephalopathy is a rare but potentially fatal condition, that can occur after obesity surgery.
Case Report: A 43-year-old Caucasian woman, with history of omega-loop gastric bypass, with hydrops, dyspnoea and severe malnutrition was referred for evaluation. After admission to medical department, she experienced three episodes of coma, and biochemical investigations showed hyperammonemia, hypoalbuminemia and hyperglutaminemia. Etiological investigations were not in favour of a urea cycle disorder, but rather a nutritional catastrophe with severe malnutrition secondary to the omega-loop gastric bypass.
Discussion: In patients with history of obesity surgery, encephalopathy symptoms should lead to look after hyperammonemia and malnutrition.
Conclusion: This report demonstrates the importance of ammonemia testing in case of neurological symptoms in patients with a history of obesity surgery.
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http://dx.doi.org/10.1016/j.clnesp.2025.03.165 | DOI Listing |
Antibiotics (Basel)
July 2025
Department of Periodontology and Oral Mucosa Diseases, Poznan University of Medical Sciences, 61-701 Poznan, Poland.
: The oral microbiome differs in obese patients compared to normal-weight subjects. Microbiologic shifts very often appear after surgical interventions such as bariatric surgery (BS) and in immunocompromised patients. However, the oral microbiome composition and load in subjects after bariatric surgery are unclear.
View Article and Find Full Text PDFInn Med (Heidelb)
May 2025
Abteilung für Allgemein- und Viszeralchirurgie, Dr. Lubos Kliniken Bogenhausen/Pasing, Denninger Str. 44, 81679, München, Deutschland.
Surgical procedures form an integral part of the interdisciplinary treatment of morbid obesity and its associated complications. The objective goes beyond mere weight control (bariatric surgery) and includes controlling the entire metabolism. Bariatric/metabolic procedures have not only become the currently most effective form of treatment for diabetes mellitus type 2 (DMT2) particularly in obese patients, but it has also proven to be a key tool for many other obesity-related secondary diseases.
View Article and Find Full Text PDFClin Nutr ESPEN
June 2025
Department of Endocrinology-Diabetology-Nutrition, Home Parenteral Nutrition Centre, CHU Rennes, Rennes, France; INRAE, INSERM, Univ Rennes, NuMeCan, Nutrition Metabolisms Cancer, Rennes, France. Electronic address:
Background: Hyperammonemic encephalopathy is a rare but potentially fatal condition, that can occur after obesity surgery.
Case Report: A 43-year-old Caucasian woman, with history of omega-loop gastric bypass, with hydrops, dyspnoea and severe malnutrition was referred for evaluation. After admission to medical department, she experienced three episodes of coma, and biochemical investigations showed hyperammonemia, hypoalbuminemia and hyperglutaminemia.
Int J Obes (Lond)
January 2025
Key Laboratory of Endocrinology of National Health Commission, Department of Endocrinology, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, 100730, China.
Objective: This study aimed to systematically review the existing literature to summarize the incidence and risk factors of post-metabolic and bariatric surgery hypoglycemia (MBSH).
Methods: We searched PubMed, Medline, Embase, and the Cochrane Library databases for the studies published from inception to August 2023. Randomized controlled trials and analytical studies that investigated the incidence or risk factors of MBSH after different surgery techniques (including Roux-en-Y gastric bypass, sleeve gastrectomy, gastric banding, duodenal switch, omega-loop gastric bypass, and vertical banded gastroplasty) were involved.
J Surg Case Rep
March 2024
Department of Surgery, St George Hospital, Grey St, Kogarah, NSW 2217, Australia.
The aim of this report is to describe the management of an iatrogenic diaphragmatic eventration following surgery to relieve neurogenic symptoms of thoracic outlet syndrome in a patient with a prior history of sleeve gastrectomy. We discuss the case of a 46-year-old woman with a 6-month history of gastro-oesophageal reflux and dyspnoea. Imaging demonstrated a left hemidiaphragm eventration and hiatus hernia.
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