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http://dx.doi.org/10.1097/TP.0000000000005374 | DOI Listing |
Disabil Rehabil
September 2025
Yang Memorial Methodist Social Service, Hong Kong SAR, China.
Purpose: This study aimed to develop an ICF core set for assessing stroke survivors in community-based rehabilitation settings in Hong Kong.
Material And Methods: A three-round Delphi process which involved 39 multidisciplinary experts in community-based rehabilitation services was conducted to reach consensus on a preliminary version of ICF core set for stroke survivors. The initial questionnaire included 130 second-level ICF categories while the panel was invited to suggest additional categories.
Disabil Rehabil
September 2025
Department of Kinesiology and Health Sciences, University of Waterloo, Waterloo, ON, Canada.
Purpose: To develop a comprehensive ICF Core Set (ICF-CS) for vertebral fragility fracture.
Materials And Methods: The development of ICF-CSs involves three phases: i) systematic literature review and qualitative studies; ii) linking process to identify the ICF codes and categories; iii) international consensus process. i) We performed a literature search and qualitative studies with people with vertebral fragility fractures and healthcare professionals; ii) We linked the findings from the search and qualitative studies to the ICF categories, and drafted the proposed ICF-CS; iii) We performed an international consensus process involving experts with clinical or research experience in management of vertebral fragility fractures.
Cell Discov
September 2025
Obstetrics and Gynecology Hospital, Institute of Reproduction and Development, Fudan University, Shanghai, China.
Adverse intrauterine environments, such as hyperglycemia, impair sexual reproduction and species continuity, yet the underlying mechanisms remain poorly understood. In this study, we demonstrated that intrauterine hyperglycemia significantly disrupted primordial germ cell (PGC) development, especially in female offspring, thus reducing fertility. Using Oct4-EGFP transgenic mice with intrauterine hyperglycemia exposure, we revealed that hyperglycemia compromised sexually specific chromatin accessibility and DNA methylation reprogramming during PGC development.
View Article and Find Full Text PDFJMIR Res Protoc
September 2025
Guangxi Key Laboratory of AIDS Prevention and Treatment, School of Public Health & Life Science Institute, Guangxi Medical University, Nanning, China.
Background: The 23-valent pneumococcal polysaccharide vaccine reduces the risk of pneumonia among adults by 38% to 46%. However, only a few older adults in resource-limited areas of China have received the pneumococcal vaccination. Pay-it-forward is a social innovation that offers participants free or subsidized health services and a community-engaged message, with an opportunity to donate to support subsequent recipients.
View Article and Find Full Text PDFMicrobiol Spectr
September 2025
King Abdullah International Medical Research Center, Jeddah, Saudi Arabia.
Recently, to achieve cure, physicians have been resorting to overuse or misuse of antimicrobials to treat resistant infections, leading to the emergence of further resistant organisms. To overcome this issue, antimicrobial guidelines have been developed. Nevertheless, recently, controversy regarding the effect of adherence to antimicrobial guidelines on patient outcomes has been raised.
View Article and Find Full Text PDF