Erasable and Multifunctional On-Skin Bioelectronics Prepared by Direct Writing.

The field of bioelectronics has witnessed significant advancements, offering practical solutions for personalized healthcare through the acquisition and analysis of skin-based physical, chemical, and electrophysiological signals. Despite these advancements, current bioelectronics face several challenges, including complex preparation procedures, poor skin adherence, susceptibility to motion artifacts, and limited personalization and reconfigurability capabilities. In this study, we introduce an innovative method for fabricating erasable bioelectronics on a flexible substrate coating adhered to the skin using a ballpoint pen without any postprocessing. Our approach yields devices that are thin, erasable, reconfigurable, dry-friction resistant, self-healing, and highly customizable. We demonstrate the multifunctionality of these on-skin bioelectronics through their application as strain sensors for motion monitoring, temperature and humidity sensors for breath monitoring, and heating elements for target point hyperthermia. The potential of our bioelectronics in personalized medicine is substantial, particularly in health monitoring. We provide a novel solution for achieving efficient and convenient personalized medical services, addressing the limitations of existing technologies and paving the way for next-generation wearable health devices.