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Purpose: To compare abutment and scan body subsidence and determine the appropriate tightening torque value for a scan body that can accurately replicate abutment subsidence.
Methods: An internally tapered connection implant was placed in a bone model. The titanium abutment (Ti Abut), polyetheretherketone scan body (PEEK SB), and titanium scan body (Ti SB) were tightened to torque values of 10 or 35 Ncm, with the 10 Ncm models used as reference models. Both the 10 and 35 Ncm models were scanned using a laboratory scanner. The vertical displacements of the Ti Abut, PEEK SB, and Ti SB at each torque value were determined using three-dimensional analysis software.
Results: Upon tightening the scan bodies and abutment to 35 Ncm, the displacement was significantly greater than when tightened to 10 Ncm (P < 0.01). At 35 Ncm, Ti SB and Ti Abut showed significantly greater displacements than PEEK SB, whereas no significant difference was observed between Ti SB and Ti Abut.
Conclusions: The titanium scan bodies, when tightened at 35 Ncm, accurately replicated titanium abutment subsidence, unlike the PEEK scan bodies.
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http://dx.doi.org/10.2186/jpr.JPR_D_24_00224 | DOI Listing |
Ir J Med Sci
September 2025
Sri Venkateswara Institute of Medical Sciences, Tirupati, India.
Introduction: Information on tertiary hyperparathyroidism (THPTH) among chronic kidney disease (CKD) patients on haemodialysis in developing countries such as India is limited, and the mortality among them remains a query.
Materials And Methods: This was a prospective cohort study conducted in at a tertiary care centre from June 2017 to June 2022. The index of suspicion for tertiary hyperparathyroidism was when investigations revealed high serum calcium and high alkaline phosphatase along with new onset of body aches, joint pains, and difficulty in walking.
J Prosthodont
September 2025
Department of Graphic Design and Engineering Projects, Faculty of Engineering Gipuzkoa, University of the Basque Country UPV/EHU, San Sebastian, Spain.
Purpose: The aim of this in vitro study was to assess whether the accuracy (trueness and precision) of full-arch implant digital impressions can be improved by replacing standard digital impressions (StDIs) with segmented digital impressions (SgDIs), obtained by superimposing short-span digital impressions using a geometric pattern.
Materials And Methods: The study was conducted using a commercial edentulous maxillary model with four implants-positioned at the sites of the canines and second molars-and four commercial intraoral scan bodies (ISBs) screwed to them. Ten StDIs and SgDIs of the model were obtained, and their accuracy was evaluated and compared in terms of trueness and precision, based on measurements of three distances and three angles between the ISBs.
Cancer Immunol Immunother
September 2025
Department of Nuclear Medicine and Molecular Imaging, Lausanne University Hospital, CHUV/UNIL, 1011, Lausanne, Switzerland.
Background: Immunotherapy is a mainstay in the treatment of patients with advanced melanoma. Yet, resistance mechanisms exist, and tumour-associated macrophages (TAMs), particularly the M2-like phenotype, are associated with poorer outcomes, with CD206 serving as their specific marker. We present the first human SPECT/CT study to visualize CD206 + TAMs in patients undergoing immunotherapy and compare the findings to clinical outcomes (NCT04663126).
View Article and Find Full Text PDFAlzheimers Dement
September 2025
Department of Clinical and Health Psychology, University of Florida, Gainesville, Florida, USA.
Introduction: Glial fibrillary acidic protein (GFAP) may contribute to Alzheimer's pathology at early disease stages. GFAP moderation of Alzheimer's disease (AD)-related neurodegeneration and cognition is unclear.
Methods: We examined plasma GFAP moderation of AD biomarkers (amyloid beta [Aβ]-positron emission tomography [PET][A]; plasma phosphorylated tau-181 [p-tau181][T]), neurodegeneration (plasma NfL[N]; structural magnetic resonance imaging [MRI][N]), and cognition (Cog; Cog) in two cohorts: University of California San Francisco (UCSF) (N = 212, 91.
Front Oncol
August 2025
Stroke Unit, Emergency Department, Umberto I Hospital, Sapienza University of Rome, Rome, Italy.
The association between ischemic stroke (IS) and malignancy is well established. Cancer-related strokes are predominantly embolic and classified as embolic strokes of undetermined source (ESUS). While malignancy-associated coagulopathy represents the primary pathogenic mechanism, neoplastic embolization of circulating tumor cells is another potential etiology, particularly in cases of cardiac and pulmonary malignancies.
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