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http://dx.doi.org/10.1093/europace/euaf065 | DOI Listing |
Pharmacol Ther
August 2025
Institute of Biochemistry and Molecular Biology, University of Hamburg, Hamburg, Germany. Electronic address:
Nonsense mutations - associated with many devastating genetic disorders that currently lack effective treatments - prematurely terminate protein synthesis by converting an amino acid-encoding sense codon into a termination codon. Transfer RNAs (tRNAs), essential players in protein synthesis, have naturally evolved to decode sense codons, while avoiding the three stop codons (UGA, UAG, and UAA) that signal termination of translation. Emerging therapeutic strategies increasingly focus on refactoring natural tRNAs into suppressor tRNAs (sup-tRNAs).
View Article and Find Full Text PDFInt J Sports Physiol Perform
September 2025
Department of Medicine and Aging Sciences, University "G. d'Annunzio" of Chieti-Pescara, Chieti, Italy.
Purpose: Focus-of-attention (FOA) research typically supports an external focus (EF) over internal focus (IF) for motor learning and performance. However, task-specific factors such as athletes' techniques and training goals may influence FOA efficacy. This study compared the effects of FOA strategies-idiosyncratic core component (ICC), EF, and IF-on explosive isometric back squats (EIBS) and squat jumps (SJ) in skilled basketball athletes.
View Article and Find Full Text PDFJ Funct Morphol Kinesiol
June 2025
Department of Sport Sciences, Kore University, Cittadella Universitaria, 94100 Enna, Italy.
: Basketball carries a high risk of both chronic and acute musculoskeletal injuries, affecting various parts of the body. Additionally, stress is a critical factor that influences athletic performance, particularly in high-pressure sports like basketball. This study aimed to investigate the impact of a specific proprioceptive training protocol on professional basketball players.
View Article and Find Full Text PDFJ Strength Cond Res
June 2025
VALFIS Research Group, Institute of Biomedicine (IBIOMED), Universidad de León, León, Spain.
Rodríguez-Fernández, A, Flórez-Gil, E, Scanlan, A, and Vaquera, A. The impact of court orientation and bout-ending mechanism on the external and internal loads of female basketball players during small-sided games. J Strength Cond Res 39(9): e1081-e1090, 2025-The aims were to examine the impact of court orientation and bout-ending mechanism on external and internal loads during small-sided basketball games (SSG) in female players and examine performance-related fatigue associated with SSG formats.
View Article and Find Full Text PDFSensors (Basel)
March 2025
VALFIS Research Group, Institute of Biomedicine (IBIOMED), Faculty of Sciences of Physical Activity and Sports, University of León, 24007 León, Spain.
This study leverages physical fitness assessment sensors to investigate the effects of a brief in-season break (detraining period) on the physical performance of female basketball players. Sixty-seven players (Senior (n = 19), U18 (n = 19), and U14 (n = 29)) were evaluated before and after a 3-week break using sensor-derived data from a countermovement jump (CMJ), an Abalakov jump (ABK), a linear speed test (20 m sprint), a seated medicine ball throw test (SMBT), and a Basketball-Specific Agility Test (TEA-Basket). The Total Score of Athleticism (TSA), computed as the mean Z-Score across tests, served as a composite indicator of physical fitness.
View Article and Find Full Text PDF