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Message: file_get_contents(https://...@gmail.com&api_key=61f08fa0b96a73de8c900d749fcb997acc09&a=1): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests
Filename: helpers/my_audit_helper.php
Line Number: 197
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File: /var/www/html/application/helpers/my_audit_helper.php
Line: 197
Function: file_get_contents
File: /var/www/html/application/helpers/my_audit_helper.php
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Function: simplexml_load_file_from_url
File: /var/www/html/application/helpers/my_audit_helper.php
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Function: getPubMedXML
File: /var/www/html/application/controllers/Detail.php
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Function: pubMedSearch_Global
File: /var/www/html/application/controllers/Detail.php
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Function: pubMedGetRelatedKeyword
File: /var/www/html/index.php
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Function: require_once
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Objectives: To evaluate the feasibility and diagnostic performance of a 3D FRACTURE (fast field echo resembling a CT using restricted echo-spacing) MRI sequence for the detection and classification of proximal tibial fractures compared with CT.
Methods: We retrospectively included 126 patients (85 male; 39.6 ± 14.5 years) from two centers following acute knee injury. Patients underwent knee MRI at 3 T including FRACTURE-MRI. Additional CT was performed in patients with tibial fractures (32.5%; n = 41) as the reference standard for fracture classification. Two radiologists independently evaluated FRACTURE-MRI for the presence of fractures and classified them according to AO/OTA, Schatzker, and the 10-segment classification. Diagnostic performance of FRACTURE-MRI was assessed using crosstabulations. Inter-reader agreement was estimated using Krippendorff's alpha. Image quality was graded on a five-point scale (5 = excellent; 1 = inadequate definition of fracture lines and fracture displacement) and assessed using estimated marginal means.
Results: Fractures were detected by FRACTURE-MRI with a sensitivity of 91.5% (83.2-96.5%) and a specificity of 97.1% (93.3-99.0%). Regarding fracture classification, diagnostic performances were slightly lower, with the 10-segment classification yielding the best sensitivity of 85.7% (81.4-89.3%) and specificity of 97.4% (96.6-98.0%), and the Schatzker classification yielding the lowest sensitivity of 78.2% (67.4-86.8%) and specificity of 97.7% (94.1-99.4%). Inter-reader agreement across the whole cohort was excellent (Krippendorff's alpha 0.89-0.96) and when considering only patients with fractures, good to acceptable (0.48-0.91). Image quality was rated good (estimated marginal mean 4.3 (4.1-4.4)).
Conclusion: FRACTURE-MRI is feasible at 3 T enabling accurate delineation of fracture lines for precise diagnosis and classification of proximal tibial fractures.
Key Points: Question CT-like MRI is increasingly being evaluated for its advantages in bone imaging but is not yet established in routine practice. Findings The 3D FRACTURE (fast field echo resembling a CT using restricted echo-spacing) MRI sequence is feasible at 3 T, allowing for diagnosis and classification of proximal tibial fractures. Clinical relevance FRACTURE-MRI might be a helpful alternative to computed tomography in an acute trauma setting by reducing costs and radiation exposure in patients requiring a preoperative MRI anyway.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC12350421 | PMC |
http://dx.doi.org/10.1007/s00330-025-11522-3 | DOI Listing |