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http://dx.doi.org/10.1038/s41371-025-00990-1 | DOI Listing |
Mater Today Bio
October 2025
University of Maribor, Faculty of Medicine, Institute of Biomedical Sciences, Taborska Ulica 8, SI-2000, Maribor, Slovenia.
Catheter associated urinary tract infection (CAUTI) is the most frequent healthcare associated infection, arising from microbial adhesion to catheter surfaces, biofilm development, and the growing problem of antimicrobial resistance. Many publications have addressed CAUTI epidemiology, biofilm biology, or biomaterials for catheters in isolation, yet there is little literature that connects these areas into a coherent translational perspective. This review seeks to fill that gap by combining an overview of biofilm pathophysiology with recent advances in material based innovations for catheter design, including nanostructured and responsive coatings, sensor enabled systems, additive manufacturing, and three dimensional printing.
View Article and Find Full Text PDFMedComm (2020)
September 2025
modulates presynaptic Ca1.3 Ca channel function in inner hair cells (IHCs) and is required for indefatigable synaptic sound encoding. Biallelic variants in are associated with non-syndromic hearing loss (DFNB93).
View Article and Find Full Text PDFBeilstein J Nanotechnol
September 2025
Department of Materials Science and Engineering, Seoul National University, Seoul, 08826 Republic of Korea.
Transient electronics are emerging as a promising class of devices designed to disappear after a defined operational period, addressing growing concerns over sustainability and long-term biocompatibility. Built from biodegradable materials that undergo hydrolysis or enzymatic degradation, these systems are particularly well suited for temporary implantable applications, such as neural monitors, wireless stimulators, and drug delivery vehicles, as well as environmentally benign electronics for soil or aquatic disposal. Despite their potential, key challenges remain in expanding the material set for diverse functionalities, achieving high-density integration for advanced operations, and enabling precise lifetime control through strategies such as protective encapsulation.
View Article and Find Full Text PDFChem Sci
September 2025
Institut für Organische Chemie, Universitat Würzburg 97074 Würzburg Germany
The reversible covalent bond formation that underpins dynamic covalent chemistry (DCC) enables the construction of stimuli-responsive systems and the efficient assembly of complex architectures. While most DCC studies have focused on systems at thermodynamic equilibrium, there is growing interest in systems that operate away from equilibrium-either by shifting to a new free-energy landscape in response to a stimulus, or by accessing an out-of-equilibrium state following an energy input. Imine-based systems are especially attractive due to the accessibility of their building blocks and their dynamic behavior in both condensation and transimination reactions.
View Article and Find Full Text PDFThere has been limited research to date into contextual factors hindering or supporting the successful implementation of neuro-affirming practice in support for Autistic and otherwise neurodivergent adults. We used a Realist Evaluation approach to explore key contexts affecting neuro-affirming practice. A preliminary programme theory of key aspects of support was developed.
View Article and Find Full Text PDF